29695-4

Leptospira interrogans sv Bulgarica Ab [Presence] in Serum

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Part Descriptions

LP28458-5   Leptospira interrogans serovar Bulgarica
Leptospira is a flexible, spiral-shaped, Gram-negative spirochete with internal flagella. Leptospira interrogans has many serovars based on cell surface antigens. Most leptospirosis infections initially present with an acute onset of fever, headache and muscle pain, which symptoms last about a week. The three organ systems most frequently involved with more significant illness are the central nervous system, kidneys, and liver, and jaundice occurs with severe infections. With the appearance of antileptospiral antibodies, the acute phase of the disease subsides and leptospires can no longer be isolated from the blood. The disease is usually biphasic, with the acute phase followed by an immune phase, which occurs after an asymptomatic period of several days. The immune phase is associated with fever and central nervous system involvement, specifically meningitis. Leptospires appear in the urine during this phase and are shed for various periods depending on the host. Severe leptospirosis is associated with progressive impairment of hepatic and renal function, and renal failure is the most common cause of death.
Leptospirosis is a worldwide zoonosis with a variety of animal hosts. The primary reservoir is wild animals such as rodents, which can shed leptospires throughout their lifetimes. Domestic animals are also an important source of human infections. The disease is more widespread in tropical countries. Direct or indirect contact with urine containing virulent leptospires is the major means by which leptospirosis is transmitted.
Leptospira species, which include L. interrogans, L. autumnalis, L. borgpetersenii, and L. weili are further divided into more than 200 serotypes based on their antigenic composition. The more severe form of leptospirosis is frequently associated with the icterohaemorrhagiae serotype and is often referred to as Weil's disease. [NCBI Books: NBK8451] Source: Regenstrief LOINC, NCBI Books: NBK8451

LP28458-5   Leptospira interrogans serovar Bulgarica
Leptospira interrogans serovar Bulgarica is sporadically found in some areas of Queensland and New South Wales, and most cases are found in southern Queensland. The main carrier is likely the rat, and probable sources of infection include contact with soil, water or other materials contaminated with the urine of an infected animal. Bulgarica is one of the rarest leptospiral serovars found in Australia, with only occasional cases reported. [https://www.health.qld.gov.au/qhcss/qhss/lepto/documents/bulgarica.pdf] Source: Mater Hospital and Health Services, Queensland Department of Health: Leptospira interrogans serovar Bulgarica

Fully-Specified Name

Component

Leptospira interrogans serovar Bulgarica Ab

Property

PrThr

Time

Pt

System

Ser

Scale

Ord

Method

Additional Names

Short Name

L inter Bulgar Ab Ser Ql

Display Name

L. interrogans sv Bulgarica Ab Ql (S)

Consumer Name Alpha Get Info

Leptospira interrogans serovar bulgarica antibody, Blood

Example Answer List: LL360-9

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.03

Last Updated

Version 2.56

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Autoantibodies
• Autoantibody
• ID
• Infectious Disease
• InfectiousDisease
• L inter
• L inter Bulgar
• L interrogans
• Leptospirosis
• Microbiology
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• Serum
• SR

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