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Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Cytomegalovirus DNA:PrThr:Pt:CSF:Ord:Probe.amp.tar
Long Common Name
Cytomegalovirus DNA [Presence] in Cerebrospinal Fluid by NAA with probe detection
Short Name
CMV DNA CSF Ql NAA+probe
Display Name
CMV DNA NAA+probe Ql (CSF)
Consumer Name Alpha Get Info
Cytomegalovirus (CMV), Spinal fluid

Part Model Get Info

  • Component
    Cytomegalovirus DNA
    LP37883-3
    • Analyte
      Cytomegalovirus DNA
      LP37883-3
      • Component Numerator
        Cytomegalovirus DNA
        LP37883-3
        • Component Numerator Core
          Cytomegalovirus
          LP14255-1
        • Component Numerator Core Suffix
          DNA
          LP32416-7
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Probe.amp.tar
    LP6464-4

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.04
Last Updated
Version 2.83 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
Order vs. Observation
Both
Common Test Rank Get Info
3868

Member of these Panels

LOINCLong Common Name
99087-9Meningitis+Encephalitis pathogens panel - Cerebrospinal Fluid by NAA with probe detection

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Cytomegalovirus DNA:Přítomnost nebo práh:Časový bod:Mozkomíšní mok:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-ATGerman (Austria)Synonyms: CMV DNA /Liquor PCR
de-DEGerman (Germany)Cytomegalie-Virus DNA:Nachweis oder Schwellenwert:Zeitpunkt:Liquor:Ordinal:Zielfragmentamplifikation mit Sondendetektion
Synonyms: CMV; Zerebrospinalflüssigkeit
el-GRGreek (Greece)Κυτταρομεγαλοϊός DNA:PrThr:Pt:ΕΝΥ:Ord:Ανιχνευτής.ενίσχυση.στόχου
Synonyms: DNA MICRO Ord PrThr Pt Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου ΕΝΥ Κυτταρομεγαλοϊός
es-ARSpanish (Argentina)ADN de citomegalovirus:concentración arbitraria:punto en el tiempo:líquido cefalorraquídeo:ordinal:sonda.amplificación.blanco
es-ESSpanish (Spain)Citomegalovirus ADN:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Sonda con amplificación dirigida
es-MXSpanish (Mexico)ADN de citomegalovirus:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CAFrench (Canada)Cytomégalovirus, ADN:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Sonde avec amplification de la cible
fr-FRFrench (France)Cytomégalovirus ADN:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:PCR amplification de cible
fr-BEFrench (Belgium)Cytomégalovirus ADN:PrThr:Temps ponctuel:LCR:Ordinal:Sonde avec amplification de la cible
Synonyms: CMV
it-ITItalian (Italy)Citomegalovirus DNA:PrThr:Pt:LCS:Ord:Sonda.amp.tar
Synonyms: Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
ko-KRKorean (Korea, Republic Of)거대세포바이러스 디옥시리보핵산:임의농도:검사시점:뇌척수액:순위척도:DNA 탐색자.증폭.표적
nl-NLDutch (Netherlands)Cytomegalovirus DNA:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:probe-detectie
Synonyms: probe.amp.tar
pl-PLPolish (Poland)Wirus cytomegalii DNA:granica wykrywalności:punkt w czasie:płyn mózgowo-rdzeniowy:uporządkowany:sonda.amplifikacja.cel
Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Cytomegalowirus DNA Cytomeglaowirusa Kwas deoksyrybonukleinowy
pt-BRPortuguese (Brazil)Citomegalovírus DNA:ACnc:Pt:LCR:Ord:Sonda com limite de detecção da amplificação de alvo
Synonyms: Deoxyribonucleic acid; CMV; Cytomgal; Cytomegalo virus; Arbitrary concentration; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Microbiology
ru-RURussian (Russian Federation)Цитомегаловирус ДНК:PrThr:ТчкВрм:ЦСЖ:Пор:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент Цереброспинальная жидкость
tr-TRTurkish (Turkey)Cytomegalovirus DNA:MevcEşik:Zmlı:BOS:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CNChinese (China)巨细胞病毒 DNA:存在情况或阈值:时间点:脑脊液:序数型:探针法.基因扩增.靶向
Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 脱氧核糖核酸探针

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=30326-3