3089-0
Urate/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP15935-7 Urate
Uric acid (urate) is a product of the metabolic breakdown of purine nucleotides. In humans, about 70% of daily uric acid disposal occurs via the kidneys.
Elevated levels of uric acid, or hyperuricemia, may be due to genetic inheritance or diet. Excess serum levels of uric acid can lead to a type of arthritis known as gout, kidney stones, cardiovascular disease, Type 2 diabetes, and metabolic syndrome. Lesch-Nyhan syndrome (LNS), an extremely rare inherited disorder, is also associated with very high serum uric acid levels. Spasticity, involuntary movement and cognitive retardation as well as manifestations of gout are seen in cases of this syndrome. LNS is due to mutations in the HPRT1 gene. To date (2012), mutations in nine other genes have been linked to the excretion of uric acid by the kidneys: SLC2A9; ABCG2; SLC17A1; SLC22A11; SLC22A12; SLC16A9; GCKR; LRRC16A; and PDZK1.
Decreased levels of uric acid, known as hypouricemia, can have numerous causes, including low dietary zinc or iron intake. Hypouricemia has been associated with multiple sclerosis (MS).
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Source: Wikipedia, Urate (Wikipedia)
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Urate/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Urate/Creat Ur
- Display Name
- Urate/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- Urate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9741
Member of these Panels
LOINC | Long Common Name |
---|---|
101929-8 | Supersaturation panel - Urine |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG34807-4 | Urate/Creatinine| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Harnsäure/Creatinin: |
de-AT | German (Austria) | Synonyms: Harnsäure/Kreatinin-Ratio /U |
es-AR | Spanish (Argentina) | urato/creatinina: |
es-MX | Spanish (Mexico) | Urato / Creatinina: |
es-ES | Spanish (Spain) | Urato/Creatinina: Synonyms: Cuantitativo |
et-EE | Estonian (Estonia) | Uraat/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
fr-FR | French (France) | Urate/créatinine: |
fr-BE | French (Belgium) | Urate/Créatinine: Synonyms: Rapport de masse |
fr-CA | French (Canada) | Urate/Créatinine: |
it-IT | Italian (Italy) | Urato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di Massa |
ko-KR | Korean (Korea, Republic Of) | 요산염/크레아티닌: |
nl-NL | Dutch (Netherlands) | uraat/creatinine: Synonyms: kreatinine |
pl-PL | Polish (Poland) | Kwas moczowy/kreatynina: |
pt-BR | Portuguese (Brazil) | Urato/Creatinina: Synonyms: UA; |
ru-RU | Russian (Russian Federation) | Урат/Креатинин: Synonyms: Количественный Масс отношение Точка во времени; |
tr-TR | Turkish (Turkey) | Ürat/Kreatinin: |
uk-UA | Ukrainian (Ukraine) | Сечова кислота/Креатинін: Synonyms: Chemistry; |
zh-CN | Chinese (China) | 尿酸/肌酐: Synonyms: CR; |
Example Units
Unit | Source |
---|---|
mg/g{creat} | Example UCUM Units |
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