LP15935-7
Urate
Active
Description
Uric acid (urate) is a product of the metabolic breakdown of purine nucleotides. In humans, about 70% of daily uric acid disposal occurs via the kidneys.
Elevated levels of uric acid, or hyperuricemia, may be due to genetic inheritance or diet. Excess serum levels of uric acid can lead to a type of arthritis known as gout, kidney stones, cardiovascular disease, Type 2 diabetes, and metabolic syndrome. Lesch-Nyhan syndrome (LNS), an extremely rare inherited disorder, is also associated with very high serum uric acid levels. Spasticity, involuntary movement and cognitive retardation as well as manifestations of gout are seen in cases of this syndrome. LNS is due to mutations in the HPRT1 gene. To date (2012), mutations in nine other genes have been linked to the excretion of uric acid by the kidneys: SLC2A9; ABCG2; SLC17A1; SLC22A11; SLC22A12; SLC16A9; GCKR; LRRC16A; and PDZK1.
Decreased levels of uric acid, known as hypouricemia, can have numerous causes, including low dietary zinc or iron intake. Hypouricemia has been associated with multiple sclerosis (MS).
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Source: Wikipedia, Urate (Wikipedia)
Basic Part Properties
- Part Display Name
- Urate
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Urate
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP15935-7
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 尿酸 Synonyms: UA |
| fr-CA | French (Canada) | Urate |
| et-EE | Estonian (Estonia) | Uraat |
| es-ES | Spanish (Spain) | Urato |
| it-IT | Italian (Italy) | Urato |
| el-GR | Greek (Greece) | Ουρικό οξύ |
| tr-TR | Turkish (Turkey) | Ürat |
| ru-RU | Russian (Russian Federation) | Урат |
| nl-NL | Dutch (Netherlands) | uraat |
| fr-BE | French (Belgium) | Urate |
| pl-PL | Polish (Poland) | Kwas moczowy |
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