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Part Descriptions

LP15747-6   Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LP29303-2   peak post extended interval dosing
Extended interval (once daily) dosing of aminoglycosides may be less nephrotoxic than conventional dosing methods. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Gentamicin^peak post extended interval dosing:MCnc:Pt:Ser/Plas:Qn:
Long Common Name
Gentamicin [Mass/volume] in Serum or Plasma --peak post extended interval dosing
Short Name
Gentamicin Pk EID SerPl-mCnc
Display Name
Gentamicin peak post extended interval dosing [Mass/Vol]
Consumer Name Alpha Get Info
Gentamicin Peak after Extended Interval Dosing, Blood

Part Model Get Info

  • Component
    Gentamicin^peak post extended interval dosing
    LP307917-7
    • Analyte
      Gentamicin
      LP15747-6
      • Component Numerator
        Gentamicin
        LP15747-6
        • Component Numerator Core
          Gentamicin
          LP15747-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      peak post extended interval dosing
      LP29303-2
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.07
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
10279

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gentamicin^Vrcholová koncentrace po prodlouženém intervalu dávkování:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Γενταμυκίνη^μέγιστο κατόπιν δόσης παρατεταμένου διαστήματος:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: DRUG/TOX MCnc Pt Qn Γενταμυκίνη μέγιστη μέγιστο κατόπιν δόσης παρατεταμένου διαστήματος Ορός Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)gentamicina^pico después de intervalo de dosificación prolongada:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ESSpanish (Spain)Gentamicina^Pico pos dosificación de aminoglucósidos en intervalo extendido o monodosis:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Gentamicina ^ pico después de la administración de intervalo extendido:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CAFrench (Canada)Gentamicine^Pic post dose intervalle prolongé:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)Gentamicine^pic après un intervalle posologique allongé:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BEFrench (Belgium)Gentamicine^Pic post dose intervalle prolongé:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-ITItalian (Italy)Gentamicina^picco post intervallo esteso di dosaggio:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Picco post intervallo esteso di dosaggio di aminog Picco TDM Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KRKorean (Korea, Republic Of)겐타마이신^연장 간격 투여 후 최고 약물 농도 시간:질량농도:검사시점:혈청/혈장:정량:
nl-NLDutch (Netherlands)gentamicine^piek na langdurige intervaldosering:massa/volume:moment:serum of plasma:kwantitatief:
pt-BRPortuguese (Brazil)Gentamicina^pico durante período de metAcolização da droga:MCnc:Pt:Sor/Plas:Qn:
Synonyms: c213; Gent; Garamycin; Genj; Genirr; Pk EID; Post-dose; Postdose; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; PST; After; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RURussian (Russian Federation)Гентамицин^пик после расширения интервала дозирования:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Gentamisin^Pik uzatilmis aralikli dozlama:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: pik
zh-CNChinese (China)庆大霉素^在延长时间间隔剂量给药之后的波峰:质量浓度:时间点:血清/血浆:定量型:
Synonyms: EID XXX刺激 - 在...之后 一剂药物的后剂量(Postdose);剂量药物的后剂量(Postdose);后剂量(Postdose);峰值;曲线上的最大值;最高点;治疗药物监测 - 波峰 之后于... 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 在...以后 在后 在延长时间间隔剂量给予氨基糖苷类药物之后的波峰;在延长时间间隔定量给予氨基糖苷类药物之后的波峰;在延长时间间隔定量给药之后的波峰 延长时间间隔给药（Extended interval dosing，EID） 延长时间间隔给药剂量给药 延长间隔给药 延长间隔给药剂量给药 时刻;随机;随意;瞬间 正泰霉素;艮他霉素 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

UnitSource
mg/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=31091-2