31091-2
Gentamicin [Mass/volume] in Serum or Plasma --peak post extended interval dosing
Active
Part Descriptions
LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275]
Source: Regenstrief LOINC
LP29303-2 peak post extended interval dosing
Extended interval (once daily) dosing of aminoglycosides may be less nephrotoxic than conventional dosing methods.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Gentamicin^peak post extended interval dosing
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Gentamicin [Mass/volume] in Serum or Plasma --peak post extended interval dosing
- Short Name
- Gentamicin Pk EID SerPl-mCnc
- Display Name
- Gentamicin peak post extended interval dosing [Mass/Vol]
- Consumer Name Alpha Get Info
- Gentamicin Peak after Extended Interval Dosing, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.07
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 10279
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Γενταμυκίνη^μέγιστο κατόπιν δόσης παρατεταμένου διαστήματος: Synonyms: MCnc Γενταμυκίνη |
es-AR | Spanish (Argentina) | gentamicina^pico después de intervalo de dosificación prolongada: |
es-ES | Spanish (Spain) | Gentamicina^Pico pos dosificación de aminoglucósidos en intervalo extendido o monodosis: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Gentamicina ^ pico después de la administración de intervalo extendido: |
fr-CA | French (Canada) | Gentamicine^Pic post dose intervalle prolongé: |
fr-FR | French (France) | Gentamicine pic après un intervalle posologique allongé: |
fr-BE | French (Belgium) | Gentamicine^Pic post dose intervalle prolongé: |
it-IT | Italian (Italy) | Gentamicina^picco post intervallo esteso di dosaggio: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Picco post intervallo esteso di dosaggio di aminog Picco TDM Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 겐타마이신^연장 간격 투여 후 최고 약물 농도 시간: |
nl-NL | Dutch (Netherlands) | gentamicine^piek na langdurige intervaldosering: |
pt-BR | Portuguese (Brazil) | Gentamicina^pico durante período de metAcolização da droga: Synonyms: c213; |
ru-RU | Russian (Russian Federation) | Гентамицин^пик после расширения интервала дозирования: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Gentamisin^Pik uzatilmis aralikli dozlama: |
zh-CN | Chinese (China) | 庆大霉素^在延长时间间隔剂量给药之后的波峰: Synonyms: EID XXX刺激 - 在...之后 一剂药物的后剂量(Postdose); |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
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