Version 2.80

Part Descriptions

LP28754-7   Ganglioside GQ1b
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. PMID: 21214559 Source: Regenstrief LOINC , PMID: 2121455

LP38231-4   Ganglioside GQ1b Ab
Anti-GQ1b are found in Miller-Fisher syndrome. Studies of these antibodies reveal large disruption of the Schwann cells. Anti-GQ1b IgG levels were elevated in patients with ophthalmoplegia in Guillain-Barré syndrome. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ganglioside GQ1b Ab
Property
Titr
Time
Pt
System
Ser
Scale
SemiQn
Method

Additional Names

Long Common Name
Ganglioside GQ1b Ab [Titer] in Serum
Short Name
GQ1b Gangl Ab Titr Ser
Display Name
Ganglioside GQ1b Ab (S) [Titer]
Consumer Name Alpha Get Info
Ganglioside GQ1b antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.07
Last Updated
Version 2.75 (MAJ)
Order vs. Observation
Observation
Common Test Rank Get Info
7197

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Γαγγλιοσίδη GQ1b Αντίσωμα:Titr:Pt:Ορός:Ημιποσοτική:
Synonyms: Titr Γαγγλιοσίδη Γαγγλιοσίδη GQ1b
es-AR Spanish (Argentina) anticuerpo contra gangliósido GQ1B:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:
es-ES Spanish (Spain) Gangliósido GQ1b Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Gangliósido GQ1b Ab:Título:Punto temporal:Suero:Cuantitativo:
fr-CA French (Canada) Ganglioside GQ1b, Ac:Titre:Temps ponctuel:Sérum:SemiQn:
fr-FR French (France) Ganglioside GQ1b anticorps:Titre:Ponctuel:Sérum:Semi-Quantitatif:
it-IT Italian (Italy) Ganglioside GQ1b Ab:Titr:Pt:Siero:SemiQn:
Synonyms: anticorpo Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo
ko-KR Korean (Korea, Republic Of) 강글리오시드 GQ1b 항체:역가:검사시점:혈청:정량:
nl-NL Dutch (Netherlands) ganglioside GQ1b As:titer:moment:serum:semikwantitatief:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Gangliosideo GQ1b Ac:Título:Pt:Soro:Qn:
Synonyms: ; GQ1b Gangl; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
zh-CN Chinese (China) 神经节苷脂 GQ1b 抗体:滴定度:时间点:血清:半定量型:
Synonyms: Ab;自身抗体 GQ1b;神经节糖苷 GQ1b 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 神经节糖苷 神经节苷脂 GQ1b Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
titer REGENSTRIEF
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=31164-7