3174-0
Antithrombin [Units/volume] in Platelet poor plasma by Chromogenic method
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Part Descriptions
LP15394-7 Antithrombin
Antithrombin is a small molecule that inactivates several enzymes of the coagulation system. It is a glycoprotein produced by the liver.
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Source: Wikipedia, Antithrombin (Wikipedia)
LP15394-7 Antithrombin
Antithrombin and antithrombin III refer to the same thing but today, however, antithrombin is the correct name. Antithrombin is a small glycoprotien, produced in the liver that inactivates several enzymes of the coagulation system including thrombin as well as factors Xa, IXa, XIa, XIIa, and kallikrein. Heparan sulfate (heparin), located on endothelial cells, binds to antithrombin causing a conformational change that results in its activation. Antithrombin deficiency is present in 0.17% of the general population. It accounts for 1.1% of unselected patients with venous thrombosis and up to 5% of patients younger than 70 years with thrombosis. Over 127 mutations in the antithrombin gene are known to cause hereditary antithrombin deficiency. Individuals heterozygous for antithrombin deficiency have a fivefold increased risk for venous thrombosis. Homozygous deficiencies are usually fatal.
Source: Regenstrief Help
Fully-Specified Name
- Component
- Antithrombin
- Property
- ACnc
- Time
- Pt
- System
- PPP
- Scale
- Qn
- Method
- Chromo
Additional Names
- Short Name
- AT III PPP Chro-aCnc
- Display Name
- Antithrombin Chromogenic method Qn (PPP)
- Consumer Name Alpha Get Info
- Antithrombin, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 3453
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 98125-8 | Intravascular coagulation and fibrinolysis panel |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Antithrombin: Synonyms: AT |
| es-AR | Spanish (Argentina) | antitrombina: |
| es-ES | Spanish (Spain) | Antitrombina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Antitrombina: |
| et-EE | Estonian (Estonia) | Antitrombiin: Synonyms: Juhuslik Kvantitatiivne Trombotsüütidevaene plasma |
| fr-CA | French (Canada) | Antithrombine: |
| fr-FR | French (France) | Antithrombine: |
| fr-BE | French (Belgium) | Antithrombine: |
| it-IT | Italian (Italy) | Antitrombina: Synonyms: Concentrazione Arbitraria Cromogenico (Enzima) Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione |
| ko-KR | Korean (Korea, Republic Of) | 항트롬빈: |
| nl-NL | Dutch (Netherlands) | antitrombine: Synonyms: coagulatiemethode |
| pt-BR | Portuguese (Brazil) | Antitrombina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Антитромбин: Synonyms: Количественный Обеднённая пластинками плазма; |
| tr-TR | Turkish (Turkey) | Antitrombin: |
| uk-UA | Ukrainian (Ukraine) | Антитромбін: Synonyms: Anti thrombin; |
| zh-CN | Chinese (China) | 抗凝血酶: Synonyms: AT; |
Example Units
| Unit | Source |
|---|---|
| U/mL | eCHN |
| units/mL | REGENSTRIEF |
| [IU]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=3174-0
LOINC Copyright
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