32160-4
Carboxyhemoglobin [Presence] in Blood by Screen method
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Part Description
LP21418-6 Carboxyhemoglobin
Carboxyhemoglobin, a complex of hemoglobin and carbon monoxide, is a marker of exposure to inhaled carbon monoxide (CO). CO gas is produced from almost any fire as the result of incomplete combustion to CO2, and the normal individual will have about 1 or 2 % of their hemoglobin in the form of carboxyhemoglobin, and up to 5% depending on environmental circumstances. Smokers can have levels as high as 10% or even higher. Poisoning with CO generally results from improperly vented furnaces, automobile exhaust, and fires, with carboxyhemoglobin:hemoglobin ratios of 10-30% found in symptomatic individuals and 30-90% in fatalities. With a 230 fold greater affinity, inhaled CO avidly replaces oxygen at its hemoglobin binding site. In addition, replacing even one of the 4 sites of the hemoglobin tetramer with CO prevents dissociation of the remaining 3 oxygen moieties to tissue (known as left shift of O2 dissociation curve). As a result, hemoglobin remains red and skin color is rosy despite physiologic anoxia. Although measuring carboxyhemoglobin can confirm carbon monoxide poisoning, the level does not always correlate with the clinical picture; carbon monoxide poisoning involves other mechanisms as well, including binding to myoglobin, cytochrome oxidase, and direct effects on the central nervous system.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Carboxyhemoglobin:
PrThr: Pt: Bld: Ord: Screen - Long Common Name
- Carboxyhemoglobin [Presence] in Blood by Screen method
- Short Name
- COHgb Bld Ql Scn
- Display Name
- Carboxyhemoglobin Screen Ql (Bld)
- Consumer Name Alpha Get Info
- Carboxyhemoglobin, Blood
Part Model Get Info
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.07
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- The scale has been changed from ACnc to reflect new model for ordinal terms; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 17672
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Karboxyhemoglobin: |
| de-DE | German (Germany) | Carboxyhämoglobin: Synonyms: COHb; |
| el-GR | Greek (Greece) | Καρβοξυαιμοσφαιρίνη: Synonyms: CHEM Ord PrThr Pt Αίμα Έλεγχος Καρβοξυαιμοσφαιρίνη |
| es-AR | Spanish (Argentina) | carboxihemoglobina: |
| es-ES | Spanish (Spain) | Carboxihemoglobina: |
| es-MX | Spanish (Mexico) | Carboxihemoglobina: |
| fr-CA | French (Canada) | Carboxyhémoglobine: |
| fr-FR | French (France) | Carboxyhémoglobine: |
| fr-BE | French (Belgium) | Carboxyhémoglobine: Synonyms: HbCO |
| it-IT | Italian (Italy) | Carbossiemoglobina: Synonyms: Chimica Presenza o Soglia Punto nel tempo (episodio) Sangue Screening tossicologico |
| ko-KR | Korean (Korea, Republic Of) | 일산화탄소 혈색소: |
| nl-NL | Dutch (Netherlands) | carboxyhemoglobine: |
| pl-PL | Polish (Poland) | Karboksyhemoglobina: Synonyms: Karboksyhemoglobina |
| pt-BR | Portuguese (Brazil) | Carboxihemoglobina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Карбоксигемоглобин: Synonyms: Кровь Порядковый Токсикологический скрининг Точка во времени; |
| tr-TR | Turkish (Turkey) | Karboksihemoglobin: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 碳氧血红蛋白: Synonyms: CO 血红蛋白; |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://