32517-5

CD3+CD8+ (T8 suppressor) cells [#/volume] in Specimen

Active

Part Descriptions

LP17728-4 Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively. Source: Regenstrief Help

LP17728-4 Cells.CD3+CD8+
HIV infection decreases the number of CD4 T-cells, also called T4 helper cells, the ratio of CD4 to CD8 T-cells and the number of CD8+ T-cells. These counts are ordered frequently to guide decisions about anti-retroviral therapy. Laboratories usually report both percentage and absolute count. When you map CD4 and CD8 markers, be careful! Since at least 1997, CDC has required the detection of both CD3+ and CD4+ to identify T4 helper cells, because the CD3 marker is needed to identify T-cell . So, any tests that report T4 helper cells are really reporting cells that carry BOTH the CD3+ and the CD4+ markers. The measure name may be CD3+ CD4+ cells, CD4+ marker, T4 cells or even just CD4+ (a misnomer). Exactly analogous rules apply to CD8+. Measures that include only CD4 or only CD8 in their name are really measuring CD3+CD4+ cells or CD3+CD8+ cells, respectively and should be reported with the LOINC code that includes both of those markers. The panel named T cell subsets will usually contain both CD3 + CD4 and CD3 + CD8 counts. These names assume that one has already gated to lymphocytes only. Lymphocytes are identified by CD45 markers. So a CD45+CD3+CD4+ is a more complicated way to name CD3+C4+ cells and in the context of looking for CD4 helper T cells they are the same . The same applies to other flow cytometer measures that are looking only at lymphocytes (B-cells, NK cells, etc). Source: Regenstrief Help

LP17729-2 CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cells.CD3+CD8+:NCnc:Pt:XXX:Qn:
Long Common Name: CD3+CD8+ (T8 suppressor) cells [#/volume] in Specimen
Short Name: CD3+CD8+ Cells # Spec
Display Name: CD3+CD8+ (T8 suppressor) cells (Specimen) [#/Vol]
Consumer Name Alpha Get Info: CD3+CD8+ (T8 Suppressor) Cells, Specimen

Part Model Get Info

Component
Cells.CD3+CD8+
LP17728-4
- Analyte
  Cells.CD3+CD8+
  LP17728-4
  - Component Numerator
    Cells.CD3+CD8+
    LP17728-4
    - Component Numerator Core
      Cells.CD3+CD8+
      LP17728-4
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NCnc
LP6836-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CELLMARK
Type: Laboratory
First Released: Version 2.08
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Observation
Common Test Rank Get Info: 5944

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Buňky CD3+CD8+ (T8 supresorové):Početní koncentrace:Časový bod:XXX:Kvantitativní:
el-GR	Greek (Greece)	Κύτταρα.CD3+CD8+:NCnc:Pt:XXX:Qn: Synonyms: CD3 CD8 CELLMARK NCnc Pt Qn XXX Κύτταρα Κύτταρα.CD3 Κύτταρα.CD3+CD8+
es-AR	Spanish (Argentina)	células.CD3+CD8+:concentración de número:punto en el tiempo:XXX:cuantitativo:
es-ES	Spanish (Spain)	Células CD3+CD8+:Concentración de número:Punto temporal:XXX:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Cells.CD3 + CD8 +:Concentración numérica:Punto temporal:XXX:Cuantitativo:
et-EE	Estonian (Estonia)	Rakud.CD3+CD8+:NCnc:Pt:XXX:Qn: Synonyms: Juhuslik Kvantitatiivne Täpsustamata materjal
fr-CA	French (Canada)	Cellules.CD3+CD8+:Concentration numérique:Temps ponctuel:XXX:Quantitatif:
fr-FR	French (France)	CD3+CD8+:Nombre/Volume:Ponctuel:Milieux divers:Numérique:
fr-BE	French (Belgium)	Cellules.CD3+CD8+:Concentration numérique:Temps ponctuel:XXX:Quantitatif:
it-IT	Italian (Italy)	Cellule.CD3+CD8+:NCnc:Pt:XXX:Qn: Synonyms: Cellule CD3 Cellule CD3+CD8+ Concentrazione Numerica Modelli di superficie cellulare Punto nel tempo (episodio)
ko-KR	Korean (Korea, Republic Of)	세포.CD3+CD8+:계수/부피:검사시점:XXX:정량:
nl-NL	Dutch (Netherlands)	cellen.CD3+CD8+:aantal/volume:moment:XXX:kwantitatief:
pl-PL	Polish (Poland)	Komórki.CD3+CD8+:stężenie liczbowe:punkt w czasie:XXX:ilościowy: Synonyms: CD8 Komórki CD3+CD8+ koncentracja
pt-BR	Portuguese (Brazil)	Células.CD3+CD8+:NCnc:Pt:XXX:Qn: Synonyms: ; CD3+CD8+ Cells; CD3 Cells; Cell; Cellularity; Leu-4; Leu4; T3; #; Number concentration; Count/mass; Count; AcS; CT; Acsolute; Acsolutes; Cnt; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Quantitative; QNT; Quant; Quan; Leu-2; T-8; Leu2; Suppressor T cells; T8; Tsuppressor; CELL MARKERS
ru-RU	Russian (Russian Federation)	Клетки.CD3+CD8+:КолОб:ТчкВрм:XXX:Колич: Synonyms: CD3+CD8+ (T8 клетки-супрессоры) клетки Количественный Количество в объеме Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hücreler.CD3+CD8+:SayKons:Zmlı:XXX:Kant:
zh-CN	Chinese (China)	细胞.CD3+CD8+:计数型浓度:时间点:XXX:定量型: Synonyms: CD3+CD8+细胞 CD3细胞 Leu2 Leu-2 Leu4;Leu-4;T3 T8 T-8 Tsuppressor 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项单位体积内的数量或计数;数量型浓度(单位体积);数量或计数型浓度(计数/体积);数量或计数型浓度(单位体积);计数型浓度(单位体积) 发现于抑制性 T-细胞/细胞毒性 T-细胞、一些 NK 细胞之上。与一些成熟 T-细胞肿瘤和大颗粒淋巴细胞增多症相关可用数量表示的;定量性;数值型;数量型;连续数值型标尺抑制性 T 细胞抑制性 T-细胞时刻;随机;随意;瞬间细胞含量;细胞性;细胞性质;细胞构成;细胞类细胞标志物

Example Units

Unit	Source
/uL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=32517-5

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.