32715-5

SCL-70 extractable nuclear Ab [Titer] in Serum by Immune diffusion (ID)

Active

Part Description

LP16758-2 SCL-70 extractable nuclear
Topoisomerase I (also known as Scl-70) is a nuclear enzyme that plays a role in releasing tension that is introduced in double-stranded DNA during DNA replication by transiently cleaving and rejoining one strand of the DNA duplex. Anti-Scl-70 autoantibodies are a marker of systemic sclerosis as well as other autoimmune diseases, including systemic lupus erythematosus (SLE). In patients with systemic sclerosis, anti-SCL-70 may be associated with more severe disease, and in patients with SLE, anti-SCL-70 suggests an increased risk of pulmonary hypertension and renal involvement. In general, anti-SCL-70 antibody status may help with diagnosis, treatment planning and prognosis in patients with connective tissue disease. PMID: 11229469 Source: Regenstrief LOINC, PMID: 11229469

LOINC Names Get Info

Fully-Specified Name: SCL-70 extractable nuclear Ab:Titr:Pt:Ser:SemiQn:Immune diffusion
Long Common Name: SCL-70 extractable nuclear Ab [Titer] in Serum by Immune diffusion (ID)
Short Name: ENA Scl70 Ab Titr Ser ID
Display Name: SCL-70 extractable nuclear Ab Immune diff (S) [Titer]
Consumer Name Alpha Get Info: SCL-70 extractable nuclear antibody, Blood

Part Model Get Info

Component
SCL-70 extractable nuclear Ab
LP39721-3
- Analyte
  SCL-70 extractable nuclear Ab
  LP39721-3
  - Component Numerator
    SCL-70 extractable nuclear Ab
    LP39721-3
    - Component Numerator Core
      SCL-70 extractable nuclear
      LP16758-2
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Immune diffusion
LP6322-4

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.09
Last Updated: Version 2.75 (MAJ)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG13182-7	SCL-70 extractable nuclear Ab\|Titr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Antinukleární protilátky SCL-70 extrahovatelné:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Imunodifuze (ID)
de-DE	German (Germany)	SCL-70 extrahierbarer nukleärer Ak:Titer:Zeitpunkt:Serum:Semiquantitativ:Immundiffusion Synonyms: Scl-70
el-GR	Greek (Greece)	Εκχυλίσιμα πυρηνικά SCL-70 Αντίσωμα:Titr:Pt:Ορός:Ημιποσοτική:Ανοσοδιάχυση Synonyms: Pt SERO Titr Ανοσοδιάχυση Αντίσωμα Εκχυλίσιμα πυρηνικά Εκχυλίσιμα πυρηνικά SCL-70 Ημιποσοτική Ορός Πυρηνικό
es-AR	Spanish (Argentina)	SCL-70 nuclear extraíble:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:difusión inmunitaria
es-ES	Spanish (Spain)	Antígeno nuclear extraíble SCL-70 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Inmunodifusión Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Ab nuclear extraíble SCL-70:Título:Punto temporal:Suero:Cuantitativo:Difusión inmunitaria (ID)
fr-CA	French (Canada)	SCL-70 nucléaire soluble, Ac:Titre:Temps ponctuel:Sérum:SemiQn:Immunodiffusion
fr-FR	French (France)	SCL-70 Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:Immunodiffusion
it-IT	Italian (Italy)	Nucleare estraibile SCL-70 Ab:Titr:Pt:Siero:SemiQn:Immuno diffusione Synonyms: anticorpo ENA Immuno diffusione (ID) Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo
ko-KR	Korean (Korea, Republic Of)	SCL-70 추출성 핵 항체:역가:검사시점:혈청:정량:면역 확산
nl-NL	Dutch (Netherlands)	SCL-70 extraheerbare nucleaire As:titer:moment:serum:semikwantitatief:immunodiffusie Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	SCL-70 rozpuszczalny jądrowy Ab:miano:punkt w czasie:surowica:półilościowy:immunodyfuzja Synonyms: Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała przeciwjądrowe SCL-70 rozpuszczalny jądrowy
pt-BR	Portuguese (Brazil)	SCL-7Título Ac:Título:Pt:Soro:Qn:Imunodifusão Synonyms: ; ENA Scl7Título; Scleroderma Ac; ANA; ANF; NA; Antinuclear antibody; Nuc; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; ID; Immunodiff; Immunodiffusion; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Imun; Imune; Imm; Serology
zh-CN	Chinese (China)	SCL-70 可提取性核抗体:滴定度:时间点:血清:半定量型:免疫扩散法 Synonyms: Ab;自身抗体 ANA ENA Ab ENA SCL-70 Ab ENA SCL-70 抗体 ENA SCL-70;SCL-70 可提取性核 Ag;SCL-70 可提取性核抗原;可提取性核抗原 SCL-70;皮硬化症 Ab;皮硬化症抗体;硬皮病 Ab;硬皮病抗体;硬皮症 Ab;硬皮症抗体 ENA 抗体 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原（Extractable Nuclear Antigen，ENA）;可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 NA SCL-70 可提取性核 Ab SCL-70 可提取性核 Ag Ab SCL-70 可提取性核抗原抗体免疫扩散可提取性核 Ab 可提取性核 Ag 之 Ab 可提取性核抗原 SCL-70 Ab 可提取性核抗原 SCL-70 抗体可提取性核抗原之抗体抗 ENA 抗可提取性核 Ag 抗可提取性核抗原抗核 Ab 抗核抗体抗核抗体（Antinuclear antibody，ANA）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间核;胞核皮硬化症硬皮病硬皮病（Scleroderma，SCL）硬皮症细胞核 Ab 胞核 Ab 胞核抗体血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.