32721-3
Tacrolimus [Mass/volume] in Serum or Plasma
Active
Part Descriptions
LP15182-6 Tacrolimus
Tacrolimus (also known as FK-506 or Prograf) is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis. It has strong immunosuppressive properties and is commonly used to prevent allograft rejection in transplant recipients. One of its modes of action is to prevent T-lymphocyte activation.
Source: National Library of Medicine, MeSH 2006
LP15182-6 Tacrolimus
Tacrolimus (also called FK-506 or fujimycin, Prograf, Advagraf, or Protopic) is amacrolide lactone, calcineurin inhibitor immunosuppresent used mainly after allogeneic organ transplant to lower the risk of organ rejection. It possesses strong immunosuppressive activity by preventing the activation by of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, TH2-mediated diseases such as Kimura's disease, and the skin condition vitiligo. There are potentially severe side effects from doses that are either too low or too high; inadequate tacrolimus concentrations may result in rejection of the transplanted organ, while high levels may lead to severe adverse effects includin nephrotoxicity, neurotoxicity, gastrointestinal disturbances, diabetogenesis, hypertension and malignant complications. [Wikipedia: Tacrolimus]
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Source: Wikipedia, Tacrolimus
Fully-Specified Name
- Component
- Tacrolimus
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Tacrolimus SerPl-mCnc
- Display Name
- Tacrolimus [Mass/Vol]
- Consumer Name Alpha Get Info
- Tacrolimus, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 3245
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG1025-8 | Tacrolimus| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Tacrolimus: |
| el-GR | Greek (Greece) | Τακρόλιμους: |
| es-AR | Spanish (Argentina) | tacrolimus: |
| es-ES | Spanish (Spain) | Tacrolimus: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Tacrolimus: |
| et-EE | Estonian (Estonia) | Takroliimus: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Tacrolimus: |
| fr-FR | French (France) | Tacrolimus: |
| fr-BE | French (Belgium) | Tacrolimus: |
| it-IT | Italian (Italy) | Tacrolimus: Synonyms: Concentrazione di Massa FK-506 Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 타크로리무스: |
| nl-NL | Dutch (Netherlands) | tacrolimus: |
| pt-BR | Portuguese (Brazil) | Tacrolimus: Synonyms: FK-506; |
| ru-RU | Russian (Russian Federation) | Такролимус: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Takrolimus: |
| zh-CN | Chinese (China) | 他克莫司: Synonyms: 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| ng/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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