33244-5
Guanidinoacetate [Moles/volume] in Serum or Plasma
Active
Term Description
Used to assess abnormalities in the synthesis of creatine.
Source: Regenstrief LOINC
Part Description
LP30825-1 Guanidinoacetate
Guanidinoacetate is the immediate precursor of creatine. Guanidinoacetate methyltransferase (GAMT) is the enzyme responsible for converting guanidinoacetate to creatine, and GAMT deficiency causes is a rare, autosomal recessive disorder whose manifestations include seizures, developmental delay, learning difficulties, and autism. Motor function is relatively spared. GAMT deficiency leads to elevated levels of plasma and urine guanidinoacetate, and low plasma creatine and creatinine levels. Elevated levels of guanidinoacetate in the brain are one cause of seizures in patients with GAMT deficiency. The primary treatment is creatine supplementation, which may be combined with ornithine supplementation and arginine restriction. Early diagnosis and treatment may prevent organ damage and preserve cognitive function. If the diagnosis does not occur early and brain damage has already occurred at the time of diagnosis, creatine supplementation can still help control seizures and improve quality of life. PMID: 28119378
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Guanidinoacetate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Guanidinoacetate SerPl-sCnc
- Display Name
- Guanidinoacetate [Moles/Vol]
- Consumer Name Alpha Get Info
- Guanidinoacetate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.73
- Change Reason
- Changed Plas to Ser/Plas based on documentation that ARUP can use either serum or plasma.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 12429
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 79289-5 | Creatine and guanidinoacetate panel - Serum or Plasma |
| 104537-6 | Creatine, guanidinoacetate and creatinine panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Guanidinoacetat: |
| es-AR | Spanish (Argentina) | guanidinoacetato: |
| es-ES | Spanish (Spain) | Guanidinoacetato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Guanidinoacetato: |
| et-EE | Estonian (Estonia) | Guanidinoatsetaat: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Guanidinoacétate: |
| fr-FR | French (France) | Guanidinoacétate: |
| fr-BE | French (Belgium) | Guanidinoacétate: |
| it-IT | Italian (Italy) | Guanidinoacetato: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | Guanidinoacetate: |
| nl-NL | Dutch (Netherlands) | guanidinoacetaat: |
| pt-BR | Portuguese (Brazil) | Guanidinoacetato: Synonyms: glycocyamine; |
| ru-RU | Russian (Russian Federation) | Гуанидинацетат: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Guanidinoasetat: |
| zh-CN | Chinese (China) | 胍基乙酸: Synonyms: GAA; |
Example Units
| Unit | Source |
|---|---|
| mmol/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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