Version 2.76

Part Description

LP31258-4   Clostridium botulinum toxin A
Botulinum toxin is a neurotoxin produced by Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod found on plants, in soil, water and the intestinal tracts of animals. Eight exotoxins (A, B, C1, C2, D, E, F and G) have been identified, all of which interfere with neural transmission by blocking the release of acetylcholine, the principal neurotransmitter at the neuromuscular junction. The toxins are used in the clinical management of various spastic medical conditions, strabismus and focal dystonias, hemifacial spasms, headaches, hyper-salivation and hyperhidrosis. Type A is the most potent toxin. In 2002 it was approved by the U.S. Food and Drug Administration for cosmetological uses. It is administered by injection into muscles or glands with the effects lasting approximately three months. Most patients require multiple treatments over many years and some develop tolerance to the injections due to the development of neutralizing antibodies to the toxin. Side effects are minor and transient. PMID: 20418969 Source: Regenstrief LOINC

Fully-Specified Name

Clostridium botulinum toxin A
Mouse bioassay.neutralization

Additional Names

Short Name
C bot Tox A Spec Ql MA Nt
Display Name
C. botulinum toxin A Mouse bioassay neutralization Ql (Specimen)
Consumer Name Alpha Get Info
Clostridium botulinum toxin A, Specimen

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.09
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
Order vs. Observation
Common Test Rank Get Info

Member of these Groups Get Info

LOINC Group Group Name
LG41628-5 Clostridium botulinum

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Clostridium botulinum Toxin A:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Maus-Bioassay.Neutralisation
es-AR Spanish (Argentina) toxina de Clostridium botulinum A:concentración arbitraria:punto en el tiempo:XXX:ordinal:bioanálisis en ratones.neutralización
es-ES Spanish (Spain) Toxina A del Clostridium botulinum:PrThr:Punto temporal:XXX:Ord:Bioensayo en ratones. Neutralización
es-MX Spanish (Mexico) Toxina A de Clostridium botulinum:Presencia o umbral:Punto temporal:XXX:Ordinal:Neutralización de bioensayo en ratón
fr-CA French (Canada) Toxine Clostridium botulinum A:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Test biologique sur souris.neutralisation
fr-FR French (France) Clostridium botulinum toxine A:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:Test sur souris neutralisation
fr-BE French (Belgium) Toxine Clostridium botulinum A:PrThr:Temps ponctuel:XXX:Ordinal:Test biologique sur souris.neutralisation
Synonyms: Clostridium botulinum A. Toxine Clostridium botulinum.Toxine
it-IT Italian (Italy) Clostridium botulinum, tossina A:PrThr:Pt:XXX:Ord:Saggio biologico topo.neutralizzazione
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Test biologico di neutralizzazione su topo Test biologico su topo Tossina A di Clostridium botulinum Tossina di Clostridium botulinum
ko-KR Korean (Korea, Republic Of) 클로스트리디움 보튤리늄 독소 A:임의농도:검사시점:XXX:순위척도:쥐 중화 생물학적검정법
nl-NL Dutch (Netherlands) Clostridium botulinum toxine A:aanwezigheid:moment:XXX:ordinaal:muizen-bioassay.neutralisatie
pl-PL Polish (Poland) Clostridium botulinum toksyna A:granica wykrywalności:punkt w czasie:XXX:półilościowy:biologiczny test neutralizacji przeprowadzany na myszach
Synonyms: Clostridium botulinum Toksyna A Clostridium botulinum Toksyna Clostridium botulinum
pt-BR Portuguese (Brazil) Clostridium botulinum toxina A:ACnc:Pt:XXX:Ord:Bioensaio de neutralização murino
Synonyms: ; C bot Tox A; Botox; C botulinum; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; MA Nt; Neutr; Neut; Microbiology
tr-TR Turkish (Turkey) Clostridium botulinum toksin A:MevcEşik:Zmlı:XXX:Srl:Sıçan biyoölçüm.nötralizasyon
Synonyms: Biyoassay Fare biyoölçüm Fare biyoölçüm.nötralizasyon Mevcut
zh-CN Chinese (China) 肉毒梭菌毒素 A:存在情况或阈值:时间点:XXX:序数型:小鼠生物鉴定.中和作用
Synonyms: A 型 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 中和 中和反应 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 小鼠生物检定 - 中和作用;小鼠生物检定.中和作用;小鼠生物测定 - 中和作用;小鼠生物测定.中和作用;小鼠生物测试 - 中和作用;小鼠生物测试.中和作用;小鼠生物鉴定 - 中和作用 小鼠生物检定;小鼠生物测定;小鼠生物测试 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 生物检定;生物检验;生物测定;生物测试 肉毒 A;肉毒 A 型;肉毒梭菌毒素 A 型;肉毒梭菌神经毒素 A;肉毒梭菌神经毒素 A 型;肉毒毒素 A;肉毒毒素 A 型 肉毒;肉毒梭菌神经毒素;肉毒毒素;肉毒芽孢梭菌毒素 肉毒梭状芽胞杆菌;肉毒芽孢梭菌

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