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Part Description

LP31707-0   Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Neuronal nuclear type 3 Ab:Titr:Pt:Ser:SemiQn:
Long Common Name
Neuronal nuclear type 3 Ab [Titer] in Serum
Short Name
Hu3 Ab Titr Ser
Display Name
Neuronal nuclear type 3 Ab (S) [Titer]
Consumer Name Alpha Get Info
Neuronal nuclear type 3 antibody, Blood

Part Model Get Info

  • Component
    Neuronal nuclear type 3 Ab
    LP39196-8
    • Analyte
      Neuronal nuclear type 3 Ab
      LP39196-8
      • Component Numerator
        Neuronal nuclear type 3 Ab
        LP39196-8
        • Component Numerator Core
          Neuronal nuclear type 3
          LP31707-0
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    NULL
     

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.09
Last Updated
Version 2.75 (MAJ)
Order vs. Observation
Both
Common Test Rank Get Info
2576

Member of these Panels

LOINCLong Common Name
43104-9Paraneoplastic Ab panel - Serum

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Antinukleární protilátky typu 3 neuronální:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:
el-GRGreek (Greece)Νευρωνικός πυρηνικός τύπος 3 Αντίσωμα:Titr:Pt:Ορός:Ημιποσοτική:
Synonyms: Pt SERO Titr Type Αντίσωμα Ημιποσοτική Νευρωνικό Νευρωνικό πυρηνικό Νευρωνικός πυρηνικός τύπος 3 Ορός Πυρηνικό
es-ARSpanish (Argentina)anticuerpo neuronal nuclear tipo 3:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:
es-ESSpanish (Spain)Neuronal nuclear tipo 3 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Tipo nuclear neuronal 3 Ab:Título:Punto temporal:Suero:Cuantitativo:
fr-FRFrench (France)Neurone noyau type 3 Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:
fr-CAFrench (Canada)Neuronal nucléaire de type 3, Ac:Titre:Temps ponctuel:Sérum:SemiQn:
it-ITItalian (Italy)Nucleare neuronale tipo 3 Ab:Titr:Pt:Siero:SemiQn:
Synonyms: anticorpo Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo
ko-KRKorean (Korea, Republic Of)신경 핵 3 형 항체:역가:검사시점:혈청:정량:
nl-NLDutch (Netherlands)neuronaal nucleair type 3 As:titer:moment:serum:semikwantitatief:
Synonyms: antistof; antilichaam soort
pl-PLPolish (Poland)Typ 3 neuronalny jądrowy Ab:miano:punkt w czasie:surowica:półilościowy:
Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne
pt-BRPortuguese (Brazil)Neuronal nuclear tipo 3 Ac:Título:Pt:Soro:Qn:
Synonyms: Nuc; Hu3; ANNA 3; Neuronal nuclear type III; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
zh-CNChinese (China)神经元细胞核 3 型 抗体:滴定度:时间点:血清:半定量型:
Synonyms: Ⅲ Ab;自身抗体 ANNA 3 Ab ANNA 3 抗体 ANNA 3;ANNA-3;Hu3;神经元核 3 型;神经元细胞核 3 型（Neuronal nuclear type 3，ANNA 3） ANNA-3 Ab ANNA-3 抗体 Hu3 Ab Hu3 抗体 III 三 叁 型 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 核;胞核 神经元性;神经元的 神经元核 神经元核 3 型 Ab 神经元核 3 型抗体 神经元细胞核 3 型 Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

UnitSource
titerREGENSTRIEF
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=33924-2