Version 2.80

Part Description

LP31804-5   Nucleosome
The nucleosome is the structural unit of chromatin and consists of a segment of dsDNA coiled around a histone core. Anti-chromatin autoantibodies, such as those found in patients with systemic lupus erythematosus (SLE) fall in to two categories: those directed against individual components of chromatin, such as DNA and histone, and those directed against the intact nucleosome. Traditionally anti-dsDNA antibodies have been among the ones used for diagnosis and monitoring of SLE, however, studies have shown that for some patients, the nucleosome is the primary antigen in SLE, and anti-nucleosome antibodies may provide a better reflection of disease activity. A subset of patients who are positive for anti-nucleosome antibodies but negative for anti-dsDNA antibodies may have a milder course of SLE that does not involve the kidneys. PMID: 25193804 Source: Regenstrief LOINC , PMID: 25193804

Fully-Specified Name

Component
Nucleosome Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Long Common Name
Nucleosome Ab [Units/volume] in Serum by Immunoassay
Short Name
Nucleosome Ab Ser IA-aCnc
Display Name
Nucleosome Ab IA Qn (S)
Consumer Name Alpha Get Info
Nucleosome antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.10
Last Updated
Version 2.73 (MIN)
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
6483

Member of these Groups Get Info

LOINC Group Group Name
LG13707-1 Nucleosome Ab|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Nukleosom Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Immunoassay
de-AT German (Austria) Synonyms: Nukleosomen-Antikörper EIA
el-GR Greek (Greece) Νουκλεόσωμα Αντίσωμα:ACnc:Pt:Ορός:Qn:IA
Synonyms: ACnc Νουκλεόσωμα
es-AR Spanish (Argentina) anticuerpo contra nucleosoma:concentración arbitraria:punto en el tiempo:suero:cuantitativo:enzimoinmunoanálisis
es-MX Spanish (Mexico) Ab nucleosoma:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
es-ES Spanish (Spain) Nucleosoma Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
et-EE Estonian (Estonia) Nukleosoom antikehad:Acnc:Pt:S:Qn:IA
Synonyms: Juhuslik Kvantitatiivne Seerum
fr-FR French (France) Nucléosomes anticorps:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE French (Belgium) Nucléosome Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
Synonyms: Anticorps
fr-CA French (Canada) Nucléosome, Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
it-IT Italian (Italy) Nucleosoma Ab:ACnc:Pt:Siero:Qn:IA
Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
ko-KR Korean (Korea, Republic Of) 누클리오솜 항체:임의농도:검사시점:혈청:정량:효소면역측정법
nl-NL Dutch (Netherlands) nucleosoom As:eenheid/volume:moment:serum:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
pl-PL Polish (Poland) Nukleosom Ab:stężenie w jednostkach umownych:punkt w czasie:surowica:ilościowy:metoda immunologiczna
Synonyms: Przeciwciała do nukleosomów
pt-BR Portuguese (Brazil) Nucleossomo Ac:ACnc:Pt:Soro:Qn:Imunoensaio
Synonyms: Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) Нуклеосома Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:IA
Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Nükleozom Ab:SçKons:Zmlı:Ser:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 核小体 抗体:任意型浓度:时间点:血清:定量型:免疫测定法
Synonyms: Ab;自身抗体 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 核小体 Ab 核粒 核粒 Ab 核粒抗体 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=34416-8