34416-8
Nucleosome Ab [Units/volume] in Serum by Immunoassay
Active
Part Description
LP31804-5 Nucleosome
The nucleosome is the structural unit of chromatin and consists of a segment of dsDNA coiled around a histone core. Anti-chromatin autoantibodies, such as those found in patients with systemic lupus erythematosus (SLE) fall in to two categories: those directed against individual components of chromatin, such as DNA and histone, and those directed against the intact nucleosome. Traditionally anti-dsDNA antibodies have been among the ones used for diagnosis and monitoring of SLE, however, studies have shown that for some patients, the nucleosome is the primary antigen in SLE, and anti-nucleosome antibodies may provide a better reflection of disease activity. A subset of patients who are positive for anti-nucleosome antibodies but negative for anti-dsDNA antibodies may have a milder course of SLE that does not involve the kidneys. PMID: 25193804
Source: Regenstrief LOINC, PMID: 25193804
Fully-Specified Name
- Component
- Nucleosome Ab
- Property
- ACnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
- IA
Additional Names
- Short Name
- Nucleosome Ab Ser IA-aCnc
- Display Name
- Nucleosome Ab IA Qn (S)
- Consumer Name Alpha Get Info
- Nucleosome antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.10
- Last Updated
- Version 2.73
- Change Reason
- The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 6483
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG13707-1 | Nucleosome Ab| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Nukleosomen-AK EIA |
| de-DE | German (Germany) | Nukleosom Ak: |
| es-AR | Spanish (Argentina) | anticuerpo contra nucleosoma: |
| es-MX | Spanish (Mexico) | Ab nucleosoma: |
| es-ES | Spanish (Spain) | Nucleosoma Anticuerpos: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Nukleosoom antikehad: Synonyms: Juhuslik Kvantitatiivne Seerum |
| fr-CA | French (Canada) | Nucléosome , Ac: |
| fr-BE | French (Belgium) | Nucléosome Ac: Synonyms: Anticorps |
| fr-FR | French (France) | Nucléosomes anticorps: |
| it-IT | Italian (Italy) | Nucleosoma Ab: Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| ko-KR | Korean (Korea, Republic Of) | 누클리오솜 항체: |
| nl-NL | Dutch (Netherlands) | nucleosoom As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Nukleosom Ab: Synonyms: Przeciwciała do nukleosomów |
| pt-BR | Portuguese (Brazil) | Nucleossomo Ac: Synonyms: Arbitrary concentration; |
| ru-RU | Russian (Russian Federation) | Нуклеосома Ат: Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Nükleozom Ab: Synonyms: Ak İmmünölçüm, immünoassay |
| zh-CN | Chinese (China) | 核小体 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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