Version 2.77

1968-7 Bilirubin.direct [Mass/volume] in Serum or Plasma

Term Description

Except when measured by differential light absorption, direct bilirubin included glucuronidated and albumin bound (delta) bilirubin;Method can be WET CHEMISTRY or DRY SLIDE = (TBIL-Bu)
Source: Regenstrief LOINC

Part Descriptions

LP15445-7   Bilirubin.glucuronidated+Bilirubin.albumin bound
Bilirubin is an orange-yellow pigment produced by the normal breakdown of heme, a component of the hemoglobin found in red blood cells. It is processed by the liver and excreted in bile. Conditions that cause red blood cell breakdown or interfere with liver or bile processing can cause elevated levels of bilirubin. Bilirubin exists in many forms. Non-glucuronidated bilirubin (also called unconjugated or indirect) is the breakdown product of heme and is not water-soluble. Hemolytic anemias, which cause increased red blood cell breakdown, are one cause of elevated non-glucuronidated bilirubin. Glucuronidated bilirubin (also called conjugated) is a water-soluble form of bilirubin that is made in the liver by the addition of sugar molecules to non-glucuronidated bilirubin. Conditions that affect liver function (such as hepatitis, cirrhosis and liver tumors) or physically block the bile ducts (such as gallstones) can cause elevated levels of glucuronidated bilirubin. A third form of bilirubin is that which is bound to albumin, and it is also known as delta bilirubin because it was originally identified based on the unexpected difference between the total bilirubin level and the level of glucuronidated plus non-glucuronidated bilirubin in some patient samples. Prior to the discovery of albumin-bound bilirubin, the term "direct" bilirubin was used as a synonym for glucuronidated bilirubin, but direct bilirubin is actually glucuronidated plus delta bilirubin (bilirubin covalently bound to albumin). Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Bilirubin

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component
Bilirubin.glucuronidated+Bilirubin.albumin bound
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Bilirub Direct SerPl-mCnc
Display Name
Bilirubin.direct [Mass/Vol]
Consumer Name Alpha Get Info
Bilirubin.direct, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
131

Member of these Panels

LOINC Long Common Name
34543-9 Bilirubin direct and total panel [Mass/volume] - Serum or Plasma
24324-6 Hepatic function 1996 panel - Serum or Plasma
24325-3 Hepatic function 2000 panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG6165-7 Bilirubin.glucuronidated+Bilirubin.albumin bound|MCnc|Pt|ANYBldSerPl
LG43215-9 Bilirubin.glucuronidated+Bilirubin.albumin bound|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Bilirubin.glucuronidiert+Bilirubin.Albumin gebunden:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
Synonyms: Bili
de-AT German (Austria) Synonyms: Bilirubin, direktes
el-GR Greek (Greece) Χολερυθρίνη συνδεδεμένη με γλυκουρονίδια+Χολερυθρίνη συνδεδεμένη με λευκωματίνη:Συγκέντρωση μάζας:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:
es-MX Spanish (Mexico) Bilirrubina glucuronidada + Bilirrubina ligada a albúmina:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Bilirrubina conjugada + bilirrubina unida a albúmina:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-AR Spanish (Argentina) bilirrubina.conjugada+bilirrubina.ligada a albúmina:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
fr-CA French (Canada) Bilirubine.glucuroconjuguée+bilirubine.liée à l'albumine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-BE French (Belgium) Bilirubine.glucuroconjuguée+bilirubine.liée ? l'albumine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Bilirubine conjuguée+liée à l'albumine:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Bilirubina.glucuronidata+Bbilirubina.albumina legata:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 글루쿠론산화 빌리루빈+알부민 결합 빌리루빈:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) bilirubine.geglucuronideerd + bilirubine.albuminegebonden:massa/volume:moment:serum of plasma:kwantitatief:
pl-PL Polish (Poland) Bilirubina, glukuronidowana+bilirubina, związana z albuminą:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy:
pt-BR Portuguese (Brazil) Bilirrubina.glicuronizada+Bilirrubina.ligada a albumina:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; Bilirub Direct; TBIL-Bu; Bilirubin direct; Bilirub Conj; Bc; Bilirubin glucuronides; Bilirubin conjugated; Bilirub Delta; Bili.delta; DeltAc; TBIL-(Bu+Bc); Bili-alb; Delta bilirubin; Bili; TBIL; Bilirubins; Protein.albumin; Alb; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; bnd; Associated; Chemistry
ru-RU Russian (Russian Federation) Билирубин.глюкоронат+Билирубин.альбумин связанный:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Bilirubin.glukuronize+Bilirubin.albumine bağlı:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 胆红素.葡糖醛酸化+胆红素.白蛋白结合型:质量浓度:时间点:血清/血浆:定量型:
Synonyms: Alb;清蛋白;白;白朊;蛋白素;蛋白胚乳;蛋白质.白蛋白;血液制品 - 白蛋白 Bc;Bilirub Conj;糖醛酸化胆红素;结合型胆红素;胆红素.糖醛酸化;胆红素.葡萄糖醛酸化;胆红素葡糖苷酸;胆红素葡萄糖醛酸甙;胆红素葡萄糖醛酸苷;葡糖醛酸化胆红素;葡萄糖醛酸化胆红素 Bili-alb;Bilirub Delta;Delta 胆红素;Deltab;Delta-胆红素;TBIL-(Bu+Bc);δ胆红素;δ-胆红素;总胆红素-(非结合型胆红素+结合型胆红素);白蛋白结合型胆红素 DBil;TBIL-Bu;总胆红素-结合型胆红素;直接胆红素;糖醛酸化胆红素+白蛋白结合型胆红素;结合型胆红素+白蛋白结合型胆红素;胆红素.糖醛酸化+胆红素.白蛋白结合型;胆红素.结合型+胆红素.白蛋白结合型;胆红素.葡萄糖醛酸化+胆红素.白蛋白结合型;胆红素葡糖苷酸+白蛋白结合型胆红素;胆红素葡萄糖苷酸+胆红素.白蛋白结合型;胆红素葡萄糖醛酸苷+白蛋白结合型胆红素;胆红素葡萄糖醛酸苷+胆红素.白蛋白结合型;葡糖醛酸化胆红素+白蛋白结合型胆红素 TBIL;总胆红素;胆红质 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 血清或血浆

Example Units

Unit Source
mg/dL Example UCUM Units
mg/dL REGENSTRIEF

1975-2 Bilirubin.total [Mass/volume] in Serum or Plasma

Term Description

Method can be DIRECT SPECTOPHOTOMETRY, WET CHEMISTRY or DRY SLIDE (TBIL)
Source: Regenstrief LOINC

Part Descriptions

LP15448-1   Bilirubin
Bilirubin is an orange-yellow pigment produced by the normal breakdown of heme, a component of the hemoglobin found in red blood cells. It is processed by the liver and excreted in bile. Conditions that cause red blood cell breakdown or interfere with liver or bile processing can cause elevated levels of bilirubin. Bilirubin exists in many forms. Non-glucuronidated bilirubin (also called unconjugated or indirect) is the breakdown product of heme and is not water-soluble. Hemolytic anemias, which cause increased red blood cell breakdown, are one cause of elevated non-glucuronidated bilirubin. Glucuronidated bilirubin (also called conjugated) is a water-soluble form of bilirubin that is made in the liver by the addition of sugar molecules to non-glucuronidated bilirubin. Conditions that affect liver function (such as hepatitis, cirrhosis and liver tumors) or physically block the bile ducts (such as gallstones) can cause elevated levels of glucuronidated bilirubin. A third form of bilirubin is that which is bound to albumin, and it is also known as delta bilirubin because it was originally identified based on the unexpected difference between the total bilirubin level and the level of glucuronidated plus non-glucuronidated bilirubin in some patient samples. Prior to the discovery of albumin-bound bilirubin, the term "direct" bilirubin was used as a synonym for glucuronidated bilirubin, but direct bilirubin is actually glucuronidated plus delta bilirubin (bilirubin covalently bound to albumin). Source: Regenstrief LOINC

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help Total bilirubin = direct + indirect Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Bilirubin

Observation Required in Panel

Required

Type of Entry

Question expects user entry - requires response [Q]

Fully-Specified Name

Component
Bilirubin
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Bilirub SerPl-mCnc
Display Name
Bilirubin [Mass/Vol]
Consumer Name Alpha Get Info
Bilirubin, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
22

Member of these Panels

LOINC Long Common Name
34543-9 Bilirubin direct and total panel [Mass/volume] - Serum or Plasma
98153-0 Child-Pugh panel
24322-0 Comprehensive metabolic 1998 panel - Serum or Plasma
24323-8 Comprehensive metabolic 2000 panel - Serum or Plasma
24324-6 Hepatic function 1996 panel - Serum or Plasma
24325-3 Hepatic function 2000 panel - Serum or Plasma
48796-7 Hepatitis C virus FibroSURE panel - Serum or Plasma
78698-8 Liver fibrosis score panel - Serum or Plasma Calculated by HepaScore
54232-4 Metabolic panel.large animal - Serum or Plasma
54233-2 Metabolic panel.small animal - Serum or Plasma
93691-4 Nonalcoholic steatohepatitis and fibrosis panel - Serum or Plasma
96789-3 Sequential Organ Failure Assessment SOFA

Member of these Groups Get Info

LOINC Group Group Name
LG6199-6 Bilirubin|MCnc|Pt|ANYBldSerPl
LG49848-1 Bilirubin|Pt|Ser/Plas|584.673 g/mole

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Bilirubin
de-DE German (Germany) Bilirubin:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
el-GR Greek (Greece) Χολερυθρίνη:Συγκέντρωση μάζας:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:
es-AR Spanish (Argentina) bilirrubina:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Bilirrubina:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Bilirrubina:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Bilirubiin:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-FR French (France) Bilirubine:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Bilirubine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-CA French (Canada) Bilirubine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Bilirubina:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 빌리루빈:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) bilirubine:massa/volume:moment:serum of plasma:kwantitatief:
pl-PL Polish (Poland) Bilirubina:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy:
pt-BR Portuguese (Brazil) Bilirrubina:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; Bilirub; Bili; TBIL; Bilirubins; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU Russian (Russian Federation) Билирубин:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Bilirubin:KütlKons:Zmlı:Ser/Plaz:Kant:
uk-UA Ukrainian (Ukraine) Білірубін:Масова Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:
Synonyms: Bili; Bilirubins; Billirubin; Chemistry; Hematology; Heme; Hepatology; Level; Liver; Mass Concentration; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; TBIL; UniversalLabOrders
zh-CN Chinese (China) 胆红素:质量浓度:时间点:血清/血浆:定量型:
Synonyms: TBIL;总胆红素;胆红质 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 血清或血浆

Example Units

Unit Source
mg/dL Example UCUM Units
mg/dL REGENSTRIEF