34627-0

Methylmalonate [Moles/volume] in Amniotic fluid

Active

Part Description

LP15735-1 Methylmalonate
Methylmalonate (methylmalonic acid) is measured as a second-tier assay when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screening. Methylmalonic acidemia (MMA) and propionic acidemia (PA) are defects of propionate metabolism caused by deficiencies in methylmalonyl-CoA mutase and propionyl-CoA carboxylase, respectively. The clinical phenotype of both conditions includes vomiting, hypotonia, lethargy, apnea, hypothermia, and coma. The biochemical phenotype for MMA includes elevated methylmalonic acid, propionyl carnitine and methylcitric acid, while patients with PA have elevated propionyl carnitine and methylcitric acid with normal methylmalonic acid concentrations as the enzymatic defect is upstream of methylmalonic-CoA mutase. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Methylmalonate:SCnc:Pt:Amnio fld:Qn:
Long Common Name: Methylmalonate [Moles/volume] in Amniotic fluid
Short Name: Methylmalonate Amn-sCnc
Display Name: Methylmalonate (Amn fld) [Moles/Vol]
Consumer Name Alpha Get Info: Methylmalonate, Amniotic fluid

Part Model Get Info

Component
Methylmalonate
LP15735-1
- Analyte
  Methylmalonate
  LP15735-1
  - Component Numerator
    Methylmalonate
    LP15735-1
    - Component Numerator Core
      Methylmalonate
      LP15735-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Amnio fld
LP7000-5
- System Core
  Amnio fld
  LP7000-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.11
Last Updated: Version 2.42 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Methylmalonát:Látková koncentrace:Časový bod:Amniová tekutina:Kvantitativní:
de-DE	German (Germany)	Methylmalonat:Stoffmengenkonzentration:Zeitpunkt:Amnionflüssigkeit:Quantitativ: Synonyms: Methylmalonsäure
el-GR	Greek (Greece)	Μεθύλομαλονικό οξύ:SCnc:Pt:Αμνιακό υγρό:Qn: Synonyms: CHEM Pt Qn SCnc Αμνιακό υγρό Μεθύλομαλονικό οξύ
es-AR	Spanish (Argentina)	metilmalonato:concentración de sustancia:punto en el tiempo:líquido amniótico:cuantitativo:
es-ES	Spanish (Spain)	Metilmalonato:Concentración de sustancia:Punto temporal:Fluido Ammiótico:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Malonato de metilo:Concentración de sustancias:Punto temporal:Líquido amniótico:Cuantitativo:
et-EE	Estonian (Estonia)	Metüülmalonaat:SCnc:Pt:AmnF:Qn: Synonyms: Aine kontsentratsioon Amnionivedelik Juhuslik Kvantitatiivne
fr-CA	French (Canada)	Méthylmalonate:Concentration de substance:Temps ponctuel:Liquide amniotique:Quantitatif:
fr-FR	French (France)	Méthylmalonate:Moles/Volume:Ponctuel:Liquide amniotique:Numérique:
fr-BE	French (Belgium)	Méthylmalonate:Concentration de substance:Temps ponctuel:Liquide amniotique:Quantitatif:
it-IT	Italian (Italy)	Metilmalonato:SCnc:Pt:Liquido amniotico:Qn: Synonyms: Chimica Concentrazione di Sostanza Liquido amniotico Punto nel tempo (episodio)
ko-KR	Korean (Korea, Republic Of)	메틸말로네이트:물질농도:검사시점:양수:정량:
nl-NL	Dutch (Netherlands)	methylmalonaat:mol/volume:moment:vruchtwater:kwantitatief:
pt-BR	Portuguese (Brazil)	Metilmalonato:SCnc:Pt:LiqAmni:Qn: Synonyms: MMA; Methylmalonic acid; Substance concentration; Level; Point in time; Random; Amn; Amniotic fluid; Amn fl; Amniotic flu; AF; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU	Russian (Russian Federation)	Метилмалонат:МолКонц:ТчкВрм:Амниотич ждк:Колич: Synonyms: Амниотическая жидкость Количественный Молярность;Молярная объёмная концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Metilmalonat:SubKons:Zmlı:Amniyon sv:Kant: Synonyms: Amniyon mayii
zh-CN	Chinese (China)	甲基丙二酸:物质的量浓度:时间点:羊水:定量型: Synonyms: MMA;丙二酸二甲酯;甲基丙二酸盐;甲基丙二酸盐/酯;甲基丙二酸酯克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间羊膜水;胎水

Example Units

Unit	Source
umol/L	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=34627-0

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.