Version 2.78

Part Description

LP14400-3   Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Fully-Specified Name

Component
Hepatitis C virus RNA
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
Probe.amp.tar detection limit = 50 IU/mL

Additional Names

Short Name
HCV RNA SerPl NAA DL=50-aCnc
Display Name
HCV RNA NAA+probe DL = 50 iU/mL Qn
Consumer Name Alpha Get Info
Hepatitis C virus (HCV), Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.11
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
6477

Member of these Panels

LOINC Long Common Name
75888-8 HCV RNA screening tests - Meaningful Use set

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus RNA:Arbiträre Konzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:Zielfragmentamplifikation Nachweisgrenze = 50 IU/ml
Synonyms: Hepacivirus C; HCV
es-AR Spanish (Argentina) sonda.amplificación.límite de detección objetivo < 50 IU/ml:concentración arbitraria:punto en el tiempo:suero/plasma:cuantitativo:PROBE.AMP.TAR DETECTION LIMIT < 50 IU/ML
es-ES Spanish (Spain) Virus Hepatitis C RNA:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:Sonda con objetivo límite de detección de amplificación=50IU/mL
Synonyms: Cuantitativo
es-MX Spanish (Mexico) ARN del virus de la hepatitis C:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Límite de detección de amplificación de ácido nucleico = 50 UI / mL
fr-CA French (Canada) Virus de l'hépatite C ARN:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec limite de détection de l'amplification de cible = 50 kiU/L
fr-FR French (France) Hépatite C virus ARN:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:PCR amplification de cible,limite de détection=50 UI/mL
fr-BE French (Belgium) Virus de l'hépatite C ARN:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec limite de détection de l'amplification de cible = 50 kiU/L
Synonyms: HCV
it-IT Italian (Italy) Epatite C, virus RNA:ACnc:Pt:Siero/Plasma:Qn:Sonda.amp.tar limite rilevamento = 50 IU/mL
Synonyms: Concentrazione Arbitraria Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda con limite di rilevamento dell''amplificazio Sonda di DNA Virus dell''epatite C
ko-KR Korean (Korea, Republic Of) C형 간염 바이러스 리보핵산:임의농도:검사시점:혈청/혈장:정량:DNA 탐색자.증폭 검출 한계 = 50 IU/ML
nl-NL Dutch (Netherlands) Hepatitis C-virus RNA:eenheid/volume:moment:serum of plasma:kwantitatief:probe-detectie met detectielimiet = 50 IU/mL
Synonyms: probe.amp.tar probe.amp.tar detectielimiet = 50 IU/mL
pt-BR Portuguese (Brazil) Hepatite C vírus RNA:ACnc:Pt:Sor/Plas:Qn:Sonda com limite de detecção da amplificação de alvo = 50 iU/mL
Synonyms: Ribonucleic acid; HCV; Hep C; Arbitrary concentration; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; PCR DL=50; PCR DL=50; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Hepatit; Hepatis; Microbiology; Viral load
tr-TR Turkish (Turkey) Hepatit C virüsü RNA:SçKons:Zmlı:Ser/Plaz:Kant:Porb.amf.hdf saptama sınırı = 50 IU/mL
zh-CN Chinese (China) 丙型肝炎病毒 RNA:任意型浓度:时间点:血清/血浆:定量型:探针法.基因扩增.靶向 - 检测极限 = 50 国际单位/毫升
Synonyms: C 型;丙;丙型 HCV RNA HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 Hep C RNA 丙肝病毒 RNA 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法 - 检测极限 = 50 IU/mL;探针法.基因扩增.靶向 - 检测极限 = 50 IU/mL;探针法.扩增.靶向 - 检测极限 = 50 IU/mL;探针法.扩增.靶向 - 检测极限 = 50 国际单位/毫升 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 探针靶向扩增定量型任意浓度 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 病毒载量 经过扩增的 肝 肝炎病毒 C 型 RNA 脱氧核糖核酸探针 血清或血浆

Example Units

Unit Source
[IU]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=34704-7