34738-5
K Ab [Titer] in Serum or Plasma
Active
Part Description
LP14926-7 K
Kell is highly polymorphic. It has two major codominant alleles, k and K, which result from a SNP (698C→T), and the corresponding k and K antigens differ by a single amino acid change (T193M). Mostly IgG antibodies, so IgM is uncommon. Anti-K does not bind complement. If hemolysis does occur, it is extravascular in nature. Anti-K can cause a severe hemolytic transfusion reaction and severe fetal anemia. In the RBC membrane, the Kell glycoprotein is covalently linked to the XK protein, a multipass membrane protein thought to have a role in transport. In the absence of XK, a condition called McLeod syndrome, Kell antigens are only weakly expressed and the RBCs are abnormal with spiky projections (acanthocytosis). Systemic findings include muscular dystrophy, cardiomyopathy, psychiatric disturbances, and neurological defects, such as loss of reflexes and movement disorders. The frequency of K antigens is 2% in Blacks, 9% in Caucasians, up to 25% in Arabs populations. Beck L, Blood groups and red cell antigens. NCBI Bookself [Internet Book], 2005.
Source: National Library of Medicine,
K
LOINC Names Get Info
- Fully-Specified Name
- K Ab:
Titr: Pt: Ser/Plas: SemiQn: - Long Common Name
- K Ab [Titer] in Serum or Plasma
- Short Name
- K Ab Titr SerPl
- Display Name
- K Ab [Titer]
- Consumer Name Alpha Get Info
- K antibody, Blood
Part Model Get Info
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 2.11
- Last Updated
- Version 2.75 (MAJ)
- Order vs. Observation
- Observation
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | K Ab: |
| el-GR | Greek (Greece) | K Αντίσωμα: Synonyms: BLDBK K Pt Titr Αντίσωμα Ημιποσοτική Ορός Ορός/Πλάσμα Πλάσμα |
| es-AR | Spanish (Argentina) | [anticuerpo anti - ] K [Ac]: |
| es-MX | Spanish (Mexico) | K Ab: |
| es-ES | Spanish (Spain) | K Anticuerpos: Synonyms: Semicuantitativo |
| fr-FR | French (France) | KEL1 (K) Ac: |
| fr-CA | French (Canada) | K, Ac: |
| it-IT | Italian (Italy) | K Ab: Synonyms: anticorpo Banca del sangue Plasma Punto nel tempo (episodio) Siero Siero o Plasma Titolo |
| ko-KR | Korean (Korea, Republic Of) | k 항체: |
| nl-NL | Dutch (Netherlands) | K As: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | K Ac: Synonyms: Dilution factor; |
| zh-CN | Chinese (China) | K 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |
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