34931-6

CD3+CD4+CD45RO-CD45RA- cells/cells in Blood

Active

Part Descriptions

LP32989-3 Cells.CD3+CD4+CD45RO-CD45RA-
HIV infection decreases the number of CD4 T-cells, also called T4 helper cells, the ratio of CD4 to CD8 T-cells and the number of CD8+ T-cells. These counts are ordered frequently to guide decisions about anti-retroviral therapy. Laboratories usually report both percentage and absolute count. When you map CD4 and CD8 markers, be careful! Since at least 1997, CDC has required the detection of both CD3+ and CD4+ to identify T4 helper cells, because the CD3 marker is needed to identify T-cell . So, any tests that report T4 helper cells are really reporting cells that carry BOTH the CD3+ and the CD4+ markers. The measure name may be CD3+ CD4+ cells, CD4+ marker, T4 cells or even just CD4+ (a misnomer). Exactly analogous rules apply to CD8+. Measures that include only CD4 or only CD8 in their name are really measuring CD3+CD4+ cells or CD3+CD8+ cells, respectively and should be reported with the LOINC code that includes both of those markers. The panel named T cell subsets will usually contain both CD3 + CD4 and CD3 + CD8 counts. These names assume that one has already gated to lymphocytes only. Lymphocytes are identified by CD45 markers. So a CD45+CD3+CD4+ is a more complicated way to name CD3+C4+ cells and in the context of looking for CD4 helper T cells they are the same . The same applies to other flow cytometer measures that are looking only at lymphocytes (B-cells, NK cells, etc). Source: Regenstrief Help

LP14443-3 CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides Source: Regenstrief LOINC

LP20086-2 CD45RA
Found on Naive helper T-cells, B-cells and Granulocytes
Associated with some T-cell lymphomas and some mature B-cell lymphomas Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cells.CD3+CD4+CD45RO-CD45RA-/Cells:NFr:Pt:Bld:Qn:
Long Common Name: CD3+CD4+CD45RO-CD45RA- cells/cells in Blood
Short Name: CD3+4+45RO-45RA- Cells NFr Bld
Display Name: CD3+CD4+CD45RO-CD45RA- cells/Cells (Bld)
Consumer Name Alpha Get Info: CD3+CD4+CD45RO-CD45RA- cells/cells, Blood

Part Model Get Info

Component
Cells.CD3+CD4+CD45RO-CD45RA-/Cells
LP445132-6
- Analyte
  Cells.CD3+CD4+CD45RO-CD45RA-/Cells
  LP445132-6
  - Component Numerator
    Cells.CD3+CD4+CD45RO-CD45RA-
    LP32989-3
    - Component Numerator Core
      Cells.CD3+CD4+CD45RO-CD45RA-
      LP32989-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    cells
    LP174115-8
    - Component Denominator Core
      cells
      LP174115-8
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NFr
LP6838-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CELLMARK
Type: Laboratory
First Released: Version 2.11
Last Updated: Version 2.79 (NAM)
Change Reason: Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Buňky.CD3+CD4+CD45RO-CD45RA-/100 buněk:Početní podíl:Časový bod:Krev:Kvantitativní:
el-GR	Greek (Greece)	Κύτταρα.CD3+CD4+CD45RO-CD45RA-/κύτταρα:NFr:Pt:Αίμα:Qn: Synonyms: CD3 CD4 CD45RO CELLMARK NFr Pt Qn Αίμα Κύτταρα Κύτταρα.CD3 Κύτταρα.CD3+CD4+ Κύτταρα.CD3+CD4+CD45RO+ Κύτταρα.CD3+CD4+CD45RO+CD45RA- Κύτταρα.CD3+CD4+CD45RO+CD45RA+ Κύτταρα.CD3+CD4+CD45RO-CD45RA- Κύτταρα.CD3+CD4+CD45RO-CD45RA+ Κύτταρα.CD3-CD4+
es-AR	Spanish (Argentina)	células.CD3+CD4+CD45RO-CD45RA+:fracción de un número:punto en el tiempo:sangre:cuantitativo:
es-ES	Spanish (Spain)	Células CD3+CD4+CD45RO-CD45RA-/células:Fracción numérica:Punto temporal:Sangre:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Células CD3 + CD4 + CD45RO-CD45RA- / 100 células:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
fr-CA	French (Canada)	Cellules.CD3+CD4+CD45RO-CD45RA-/Cellules:Fraction numérique:Temps ponctuel:Sang:Quantitatif:
fr-FR	French (France)	CD3+CD4+CD45RO-CD45RA-/cellules:Fraction de nombres:Ponctuel:Sang:Numérique:
it-IT	Italian (Italy)	Cellule.CD3+CD4+CD45RO-CD45RA-/cellule:NFr:Pt:Sangue:Qn: Synonyms: Cellule CD3 Cellule CD3+CD4+ Cellule CD3+CD4+CD45RO+ Cellule CD3+CD4+CD45RO+CD45RA- Cellule CD3+CD4+CD45RO+CD45RA+ Cellule CD3+CD4+CD45RO-CD45RA- Cellule CD3+CD4+CD45RO-CD45RA+ Cellule CD3-CD4+ Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
ko-KR	Korean (Korea, Republic Of)	세포.CD3+CD4+CD45RO-CD45RA-/100 세포:숫자분획:검사시점:전혈:정량:
nl-NL	Dutch (Netherlands)	cellen.CD3+CD4+CD45RO-CD45RA-/cellen:getalsfractie:moment:bloed:kwantitatief:
pl-PL	Polish (Poland)	Komórki.CD3+CD4+CD45RO-CD45RA-/komórki:frakcja liczbowa:punkt w czasie:krew:ilościowy: Synonyms: CD4 CD45RO Komórki CD3+CD4+ Komórki CD3+CD4+CD45RO+CD45RA- Komórki CD3+CD4+CD45RO+CD45RA+ Komórki CD3+CD4+CD45RO-CD45RA- Komórki CD3+CD4+CD45RO-CD45RA+
pt-BR	Portuguese (Brazil)	Células.CD3+CD4+CD45RO+CD45RA-/100 células:NFr:Pt:SgTotal:Qn: Synonyms: ; CD3+4+45RO-45RA- Cells; CD3+4+45RO-45RA+ Cells; CD3+4+45RO+45RA+ Cells; CD3+4+45RO-45RA- Cells; CD3+4+45RO+45RA- Cells; CD3+CD4+ Cells; CD3 Cells; Cell; Cellularity; UCHL-1; Leu-4; Leu4; T3; Gated cells; Fr; Number fraction; Percent; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Leu-18; Leu18; 2H4; Leu-3; T-4; Leu3; W3/25; Helper T cells; Inducer T cells; T4; L3T4; CELL MARKERS
ru-RU	Russian (Russian Federation)	Клетки.CD3+CD4+CD45RO-CD45RA-/клетки:КолДоля:ТчкВрм:Кр:Колич: Synonyms: CD3+CD4+ (T4 хэлперы) клетки Количественный Количество отношение Кровь Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hücreler.CD3+CD4+CD45RO-CD45RA-/Hücreler:SayFr:Zmlı:Kan:Kant:
zh-CN	Chinese (China)	细胞.CD3+CD4+CD45RO-CD45RA-/细胞:计数型分数:时间点:全血:定量型: Synonyms: CD3+CD4+CD45RO+CD45RA+细胞 CD3+CD4+CD45RO+CD45RA-细胞 CD3+CD4+CD45RO-CD45RA+细胞 CD3+CD4+CD45RO-CD45RA-细胞 CD3+CD4+细胞 CD3-CD4+细胞 CD3细胞 CD45RA L3T4 Leu18 Leu-18 Leu3 Leu-3 Leu4;Leu-4;T3 T4 T-4 UCHL-1 W3/25 发现于原态辅助 T-细胞、B-细胞以及粒细胞之上。与一些 T-细胞淋巴瘤和一些成熟 B-细胞淋巴瘤相关。发现于辅助 T-细胞；微弱表达于单核细胞。与相关。一些成熟 T-细胞肿瘤，包括大多数情况下的 T-细胞慢性淋巴细胞白血病/前淋巴细胞白血病、外周 T-细胞淋巴瘤、成人 T-细胞白血病/淋巴瘤以及 Sézary 综合征（T 细胞红皮病）/蕈样肉芽肿（mycosis fungoides）。可用数量表示的;定量性;数值型;数量型;连续数值型标尺数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间细胞含量;细胞性;细胞性质;细胞构成;细胞类细胞标志物血;血液诱导 T 细胞诱导性 T 细胞辅助 T 细胞辅助诱导 T 细胞辅助诱导物 T 细胞

Example Units

Unit	Source
%	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.