Version 2.78

Part Description

LP28735-6   DNA index
DNA index (DI), which is associated with DNA ploidy, is a reflection of the average amount of DNA in the tumor cells. The DI can be measured by flow cytometry or image cytometry, both of which result in a DNA ploidy histogram, where the channel number on the x-axis represents fluorescent intensity or optical density for the two methods, respectively. All cells with the same quantity of DNA form one peak on the histogram, and with a population of normal cells, the largest peak represents diploid cells in G1 of the cell cycle, and a smaller peak represents cells in G2/M-phase. When there is a mixed population of normal and tumor cells, two or more G1 peaks will be seen, one for the normal cells and one or more for the tumor cells. The DI is calculated by dividing the channel number of the tumor cell G1 peak by the channel number of the normal (diploid control) G1 peak. If the tumor cells are diploid, the DI is 1, and if the cells are aneuploid, the DI is greater than or less than 1. For example, tetraploid cells have a DI of 2 because they have twice as much DNA content as normal diploid cells, and hypodiploid tumor cells have a DI of <1. PMID: 24532190 Source: Regenstrief LOINC, PMID: 24532190

Fully-Specified Name

Component
DNA index
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
Flow cytometry

Additional Names

Short Name
DNA Index SerPl FC-aCnc
Display Name
DNA index FC Qn
Consumer Name Alpha Get Info
DNA index, Blood

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.11
Last Updated
Version 2.69
Order vs. Observation
Both

Formula (Readable)

DNA index (DI) = mean channel # of the G1 peak of the tumor/mean channel # of G1 peak of normal cells

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) pindice de ADN:concentración arbitraria:punto en el tiempo:suero/plasma:cuantitativo:citometría de flujo
es-ES Spanish (Spain) Índice del ADN:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Índice de ADN:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Citometría de flujo (FC)
fr-FR French (France) ADN index:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Cytométrie de flux
it-IT Italian (Italy) DNA, indice:ACnc:Pt:Siero/Plasma:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Concentrazione Arbitraria Indice di DNA Patologia molecolare Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 디옥시리보핵산 지수:임의농도:검사시점:혈청/혈장:정량:유세포검사
nl-NL Dutch (Netherlands) DNA index:eenheid/volume:moment:serum of plasma:kwantitatief:flowcytometrie
pt-BR Portuguese (Brazil) DNA índice:ACnc:Pt:Sor/Plas:Qn:Citometria de fluxo
Synonyms: DI; Deoxyribonucleic acid; Arbitrary concentration; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; FC; Molecular pathology
ru-RU Russian (Russian Federation) ДНК индекс:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич:Проточная цитометрия
Synonyms: ДНК отношение Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) DNA indeksi:SçKons:Zmlı:Ser/Plaz:Kant:Akış sitometri
Synonyms: Akış hücremetresi
zh-CN Chinese (China) DNA 指数:任意型浓度:时间点:血清/血浆:定量型:流式细胞测量术
Synonyms: DI;DNA 指数 = 肿瘤 G1 峰的平均通道数（mean channel #）与正常细胞平均通道数之比;DNA 指数（DNA index，DI） 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 分子病理学;分子病理学试验 动态 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 血清或血浆

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=34975-3