35139-5

Interferon beta Ab [Titer] in Serum or Plasma

Active

Part Descriptions

LP18172-4 Interferon.beta
Beta interferon is a recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta are cytokines produced by nucleated cells (predominantly natural killer cells) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes with an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral (the most important being inhibition of viral protein synthesis), antiproliferative and immune modulating effects. The recombinant therapeutic forms of interferon beta are interferon beta 1-a and interferon beta 1-b. Source: National Cancer Institute, Beta interferon

LP38708-1 Interferon.beta Ab
Highly elevated levels of neutralizing antibodies (NAbs >1:100) to interferon-beta used as therapy in patients with Multiple Sclerosis have been reported to correlate with predictable loss of interferon-beta bioactivity. In patients with elevated NAb levels from >1:20 to <1:100, interferon-beta bioactivity may still be present, but does not necessarily correlate to the exact NAb titer, and continued patient monitoring may be warranted. There is no apparent loss of interferon-beta bioactivity in patients who test positive in the binding antibody assay, but
negative for NAbs; however, continued patient monitoring may also be warranted in this instance as well. Source: Quest Diagnostics Inc., Interferon-beta 1a (IFNB-1a) Antibody

LOINC Names Get Info

Fully-Specified Name: Interferon.beta Ab:Titr:Pt:Ser/Plas:SemiQn:
Long Common Name: Interferon beta Ab [Titer] in Serum or Plasma
Short Name: IFN-B Ab Titr SerPl
Display Name: Interferon beta Ab [Titer]
Consumer Name Alpha Get Info: Interferon beta antibody, Blood

Part Model Get Info

Component
Interferon.beta Ab
LP38708-1
- Analyte
  Interferon.beta Ab
  LP38708-1
  - Component Numerator
    Interferon.beta Ab
    LP38708-1
    - Component Numerator Core
      Interferon.beta
      LP18172-4
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
NULL

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.11
Last Updated: Version 2.75 (MAJ)
Order vs. Observation: Both
Common Test Rank Get Info: 13745

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Interferon beta Ab:Arbitrární koncentrace (titr):Časový bod:Sérum/plazma:Semikvantitativní:
de-DE	German (Germany)	Interferon.beta Ak:Titer:Zeitpunkt:Serum oder Plasma:Semiquantitativ:
el-GR	Greek (Greece)	Ιντερφερόνη.β Αντίσωμα:Titr:Pt:Ορός/Πλάσμα:Ημιποσοτική: Synonyms: Pt SERO Titr Αντίσωμα Ημιποσοτική Ιντερφερόνη Ιντερφερόνη.β Ορός Ορός/Πλάσμα Πλάσμα
es-AR	Spanish (Argentina)	anticuerpo contra interferón.beta 1:factor de dilución (titulación):punto en el tiempo:suero/plasma:cuantitativo:
es-ES	Spanish (Spain)	Interferon beta Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero o Plasma:Semicuantitativo: Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Interferon.beta Ab:Título:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FR	French (France)	Interféron bêta Ac:Titre:Ponctuel:Sérum/Plasma:Semi-Quantitatif:
fr-CA	French (Canada)	Interféron.bêta, Ac:Titre:Temps ponctuel:Sérum/Plasma:SemiQn:
it-IT	Italian (Italy)	Interferone.beta Ab:Titr:Pt:Siero/Plasma:SemiQn: Synonyms: anticorpo Interferone beta Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant Titolo
ko-KR	Korean (Korea, Republic Of)	인터페론.베타 항체:역가:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	interferon.bèta As:titer:moment:serum of plasma:semikwantitatief: Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Interferon.beta Ab:miano:punkt w czasie:surowica lub osocze:półilościowy: Synonyms: IFN-beta Przeciwciała do interferonu beta
pt-BR	Portuguese (Brazil)	Interferon.beta Ac:Título:Pt:Sor/Plas:Qn: Synonyms: ; B-IFN; Betaferon; B-IFN 1A+1B; INF-B; IFN; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; B; Serology
zh-CN	Chinese (China)	干扰素.beta 抗体:滴定度:时间点:血清/血浆:半定量型: Synonyms: Ab;自身抗体 B beta 干扰素 Ab beta 干扰素;B-IFN;B-IFN 1A+1B;INF-B;β干扰素;干扰素 beta;干扰素.β;干扰素β beta 干扰素抗体 B-IFN Ab B-IFN 抗体 IFN INF-B Ab INF-B 抗体 β β干扰素 Ab β干扰素抗体干扰素 beta Ab 干扰素 beta 抗体干扰素.beta Ab 干扰素.β Ab 干扰素.β抗体干扰素β Ab 干扰素β抗体效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类血清或血浆贝塔

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.