35141-1

Purine nucleoside phosphorylase [Enzymatic activity/volume] in Cerebrospinal Fluid

Active

Part Description

LP15841-7 Purine nucleoside phosphorylase
Purine nucleoside phosphorylase (also known as PNPase) is an enzyme (EC 2.4.2.1) involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine, in each case creating ribose phosphate. NP encodes the enzyme purine nucleoside phosphorylase that, together with adenosine deaminase (ADA), serves a key role in purine catabolism, referred to as the salvage pathway. Mutations in ADA lead to an accumulation of (d)ATP, which inhibits ribonucleotide reductase, leading to a deficiency in (d)CTPs and (d)TTPs, which, in turn, induces apoptosis in T-lymphocytes and B-lymphocytes, leading to severe combined immunodeficiency (SCID).

PNP-deficient patients will have an immunodeficiency problem. It affects only T-cells; B-cells are unaffected by the deficiency. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name: Purine nucleoside phosphorylase:CCnc:Pt:CSF:Qn:
Long Common Name: Purine nucleoside phosphorylase [Enzymatic activity/volume] in Cerebrospinal Fluid
Short Name: PNP CSF-cCnc
Display Name: Purine nucleoside phosphorylase (CSF) [Catalytic activity/Vol]
Consumer Name Alpha Get Info: Purine nucleoside phosphorylase, Spinal fluid

Part Model Get Info

Component
Purine nucleoside phosphorylase
LP15841-7
- Analyte
  Purine nucleoside phosphorylase
  LP15841-7
  - Component Numerator
    Purine nucleoside phosphorylase
    LP15841-7
    - Component Numerator Core
      Purine nucleoside phosphorylase
      LP15841-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
CCnc
LP6789-4
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
CSF
LP7156-5
- System Core
  CSF
  LP7156-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.11
Last Updated: Version 2.83 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Purin-nukleosidfosforyláza:Katalytická koncentrace:Časový bod:Mozkomíšní mok:Kvantitativní:
el-GR	Greek (Greece)	Φωσφορυλάση πουρινικών νουκλεοσιδίων:CCnc:Pt:ΕΝΥ:Qn: Synonyms: CCnc CHEM Pt Qn ΕΝΥ Πουρίνη Φωσφορυλάση Φωσφορυλάση πουρινικών νουκλεοσιδίων
es-AR	Spanish (Argentina)	purina nucleósido fosforilasa:concentración catalítica:punto en el tiempo:líquido cefalorraquídeo:cuantitativo:
es-ES	Spanish (Spain)	Purin nucleósido fosforilasa:Concentración Catalítica:Punto temporal:Líquido Cefalorraquideo:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Purina nucleósido fosforilasa:Concentración catalítica:Punto temporal:Fluído espinal cerebral:Cuantitativo:
et-EE	Estonian (Estonia)	Puriini nukleosiidi fosforülaas:CCnc:Pt:CSF:Qn: Synonyms: Juhuslik Kvantitatiivne Liikvor
fr-CA	French (Canada)	Purine-nucléoside phosphorylase:Concentration catalytique:Temps ponctuel:LCR:Quantitatif:
fr-FR	French (France)	Purine nucléoside phosphorylase:Catalytique/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
fr-BE	French (Belgium)	Purine-nucléoside phosphorylase:Concentration catalytique:Temps ponctuel:LCR:Quantitatif:
it-IT	Italian (Italy)	Purina nucleoside fosforilasi:CCnC:Pt:LCS:Qn: Synonyms: Chimica Concentrazione Catalitica Liquido cerebrospinale PNPasi Punto nel tempo (episodio)
ko-KR	Korean (Korea, Republic Of)	퓨린 뉴클레오시드 포스포릴라아제:촉매농도:검사시점:뇌척수액:정량:
nl-NL	Dutch (Netherlands)	purinenucleosidefosforylase:enzymatische activiteit/volume:moment:liquor cerebrospinalis:kwantitatief:
pl-PL	Polish (Poland)	Fosforylaza nukleozydów purynowych:stężenie katalityczne:punkt w czasie:płyn mózgowo-rdzeniowy:ilościowy:
pt-BR	Portuguese (Brazil)	Purina nucleosídeo fosforilase:CCnc:Pt:LCR:Qn: Synonyms: ; PNP; Catalytic Concentration; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU	Russian (Russian Federation)	Пуриновых нуклеозидов фосфорилаза:КаталКонц:ТчкВрм:ЦСЖ:Колич: Synonyms: Каталитическая концентрация Количественный Точка во времени;Момент Цереброспинальная жидкость
tr-TR	Turkish (Turkey)	Pürin nukleozid fosforilaz:KtlKons:Zmlı:BOS:Kant:
zh-CN	Chinese (China)	嘌呤核苷酸磷酸化酶:催化浓度:时间点:脑脊液:定量型: Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 PNP 催化浓度(单位体积);单位体积内酶的单位数化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺四氮杂茚时刻;随机;随意;瞬间脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液

Example Units

Unit	Source
U/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.