35142-9

Amphiphysin Ab [Titer] in Cerebrospinal Fluid

Active

Part Descriptions

LP30843-4 Amphiphysin
Amphiphysin is a protein associated with the cytoplasmic surface of synaptic vesicles and is encoded by the AMPH gene. Patients with stiff man syndrome and breast cancer can be positive with autoantibodies against the amphiphysin protein. Source: Regenstrief LOINC

LP37039-2 Amphiphysin Ab
Paraneoplastic syndromes (PNS) are diseases associated with remote effects of tumors, of which small-cell lung cancer (SCLC), ovarian cancer, breast cancer, thymoma, Hodgkin lymphoma, and testicular cancer are the most common. Stiff-person syndrome (SPS) is a rare neurological disorder characterized by stiffness of skeletal muscles with superimposed spasms, which can have an idiopathic or paraneoplastic component. First described in women with breast cancer and SPS, amphiphysin antibodies have been reported in patients with diverse paraneoplastic neurological disorders, and cancers. Amphiphysin antibodies are considered diagnosic for paraneoplastic neurologic syndromes and can direct the search for an occult tumor, recurrence of tumor, or second tumor. Source: ARUP Laboratories

LP37039-2 Amphiphysin Ab
Amphiphysin is a brain-enriched protein normally found only within the membrane of synaptic vesicles in neural tissue. Antibodies against amphiphysin (128kDa) are directed against the protein amphiphysin, and their presence plays an important diagnostic role in paraneoplastic syndromes (e.g. Lambert Eaton myasthenia syndrome, encephalomyelitis with rigidity, cerebellar syndrome, sensory neuronopathy, opsoclonus myoclonus ataxia, and Stiff-man syndrome). Paraneoplastic syndromes are autoantibody-mediated neurologic disorders most commonly associated with cancers of the lung, breast, ovaries or lymphatic system. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Amphiphysin Ab:Titr:Pt:CSF:SemiQn:
Long Common Name: Amphiphysin Ab [Titer] in Cerebrospinal Fluid
Short Name: Amphiphysin Ab Titr CSF
Display Name: Amphiphysin Ab (CSF) [Titer]
Consumer Name Alpha Get Info: Amphiphysin antibody, Spinal fluid

Part Model Get Info

Component
Amphiphysin Ab
LP37039-2
- Analyte
  Amphiphysin Ab
  LP37039-2
  - Component Numerator
    Amphiphysin Ab
    LP37039-2
    - Component Numerator Core
      Amphiphysin
      LP30843-4
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
CSF
LP7156-5
- System Core
  CSF
  LP7156-5
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
NULL

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.11
Last Updated: Version 2.83 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 4882

Member of these Groups Get Info

LOINC Group	Group Name
LG14304-6	Amphiphysin Ab\|Titr\|Pt\|CSF

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Amfifysin Ab:Arbitrární koncentrace (titr):Časový bod:Mozkomíšní mok:Semikvantitativní:
el-GR	Greek (Greece)	Αμφιφυσίνη Αντίσωμα:Titr:Pt:ΕΝΥ:Ημιποσοτική: Synonyms: Pt SERO Titr Αμφιφυσίνη Αντίσωμα ΕΝΥ Ημιποσοτική
es-AR	Spanish (Argentina)	anticuerpo conra anfifisina:factor de dilución (titulación):punto en el tiempo:líquido cefalorraquídeo:cuantitativo:
es-MX	Spanish (Mexico)	Amphiphysin Ab:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:
es-ES	Spanish (Spain)	Anfifisina Anticuerpos:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Semicuantitativo: Synonyms: Semicuantitativo
fr-FR	French (France)	Amphiphysine Ac:Titre:Ponctuel:Liquide céphalorachidien:Semi-Quantitatif:
fr-CA	French (Canada)	Amphiphysine, Ac:Titre:Temps ponctuel:LCR:SemiQn:
it-IT	Italian (Italy)	Amfifisina Ab:Titr:Pt:LCS:SemiQn: Synonyms: anticorpo Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo
ko-KR	Korean (Korea, Republic Of)	Amphiphysin Antibody:역가:검사시점:뇌척수액:정량:
nl-NL	Dutch (Netherlands)	amfifysine As:titer:moment:liquor cerebrospinalis:semikwantitatief: Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Amfifizyna Ab:miano:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy: Synonyms: Przeciwciała do amfifizyny
pt-BR	Portuguese (Brazil)	Amfifisina Ac:Título:Pt:LCR:Qn: Synonyms: Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
zh-CN	Chinese (China)	双载蛋白抗体:滴定度:时间点:脑脊液:半定量型: Synonyms: Ab;自身抗体 Amphiphysin Ab CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液两亲蛋白;两性蛋白;Amphiphysin（一种位于神经元突触前膜的 128kD 蛋白）;神经元突触囊泡 Amphiphysin;两性蛋白(僵直人综合征伴乳腺癌128kDa 自身抗原);amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit	Source
titer	REGENSTRIEF
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.