Version 2.77

Part Description

LP31707-0   Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786 Source: Regenstrief LOINC

Fully-Specified Name

Component
Neuronal nuclear type 3 Ab
Property
Titr
Time
Pt
System
CSF
Scale
SemiQn
Method

Additional Names

Short Name
Hu3 Ab Titr CSF
Display Name
Neuronal nuclear type 3 Ab (CSF) [Titer]
Consumer Name Alpha Get Info
Neuronal nuclear type 3 antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.11
Last Updated
Version 2.75
Order vs. Observation
Both
Common Test Rank Get Info
4874

Member of these Groups Get Info

LOINC Group Group Name
LG50122-7 Neuronal nuclear type 3 Ab|Titr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) anticuerpo neuronal nuclear tipo 3:factor de dilución (titulación):punto en el tiempo:líquido cefalorraquídeo:cuantitativo:
es-ES Spanish (Spain) Neuronal nuclear tipo 3 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Semicuantitativo:
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Tipo nuclear neuronal 3 Ab:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:
fr-FR French (France) Hu3 anticorps:Titre:Ponctuel:Liquide céphalorachidien:Numérique:
fr-CA French (Canada) Neuronal nucléaire de type 3 , Ac:Titre:Temps ponctuel:LCR:SemiQn:
it-IT Italian (Italy) Nucleare neuronale tipo 3 Ab:Titr:Pt:LCS:SemiQn:
Synonyms: anticorpo Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo
ko-KR Korean (Korea, Republic Of) 신경 핵 3 형 항체:역가:검사시점:뇌척수액:정량:
nl-NL Dutch (Netherlands) neuronaal nucleair type 3 As:titer:moment:liquor cerebrospinalis:semikwantitatief:
Synonyms: antistof; antilichaam soort
pl-PL Polish (Poland) Typ 3 neuronalny jądrowy Ab:miano:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:
Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne
pt-BR Portuguese (Brazil) Neuronal nuclear tipo 3 Ac:Título:Pt:LCR:Qn:
Synonyms: Nuc; Hu3; ANNA 3; Neuronal nuclear type III; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
zh-CN Chinese (China) 神经元细胞核 3 型 抗体:滴定度:时间点:脑脊液:半定量型:
Synonyms: Ⅲ Ab;自身抗体 ANNA 3 Ab ANNA 3 抗体 ANNA 3;ANNA-3;Hu3;神经元核 3 型;神经元细胞核 3 型（Neuronal nuclear type 3，ANNA 3） ANNA-3 Ab ANNA-3 抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Hu3 Ab Hu3 抗体 III 三 叁 型 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 核;胞核 神经元性;神经元的 神经元核 神经元核 3 型 Ab 神经元核 3 型抗体 神经元细胞核 3 型 Ab 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
titer REGENSTRIEF
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=35144-5