Version 2.78

Part Description

LP16098-3   cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. PMID: 19545653 Source: Regenstrief LOINC, PMID: 19545653

Fully-Specified Name

Component
cycloSPORINE^12H post dose
Property
MCnc
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Short Name
cycloSPORINE 12h p Bld-mCnc
Display Name
cycloSPORINE 12 Hr post dose (Bld) [Mass/Vol]
Consumer Name Alpha Get Info
cycloSPORINE 12 hr after dose, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
11183

Member of these Groups Get Info

LOINC Group Group Name
LG14470-5 Cyclosporine^12H post dose|MCnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cyclosporin^12 Stunden nach Dosis:Massenkonzentration:Zeitpunkt:Blut:Quantitativ:
Synonyms: Ciclosporin
es-AR Spanish (Argentina) ciclosporina^12 horas después de la dosis:concentración de masa:punto en el tiempo:sangre:cuantitativo:
es-ES Spanish (Spain) Ciclosporina^12 horas pos-dosis:Concentración de masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) cycloSPORINE ^12H después de la dosis:Concentración de masa:Punto temporal:Sangre:Cuantitativo:
fr-CA French (Canada) Cyclosporine^12 h post dose:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-FR French (France) Ciclosporine T12h après administration:Masse/Volume:Ponctuel:Sang:Numérique:
fr-BE French (Belgium) Cyclosporine^12 h post dose:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
it-IT Italian (Italy) Ciclosporina^12h post dose:MCnc:Pt:Sangue:Qn:
Synonyms: 12 ore dopo dose Concentrazione di Massa dopo dose Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
ko-KR Korean (Korea, Republic Of) 시클로스포린^투여 후 12시간:질량농도:검사시점:전혈:정량:
nl-NL Dutch (Netherlands) ciclosporine^12 uur na dosis:massa/volume:moment:bloed:kwantitatief:
Synonyms: 12U na dosis
pt-BR Portuguese (Brazil) Ciclosporina^12 hs após dose:MCnc:Pt:SgTotal:Qn:
Synonyms: ; Cyclosporin; Cyclosporins; CsA; Ciclosporin; Ciclosporine; Neoral; SangCya; Cyclosporin a; Sandimmune; p dose; Mass concentration; Level; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Drugs; PST; After; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Циклоспорин^12 часов после дозы:МассКонц:ТчкВрм:Кр:Колич:
Synonyms: Количественный Кровь Массовая концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Siklosporin^12Sa snr dozu:KütlKons:Zmlı:Kan:Kant:
zh-CN Chinese (China) 环孢菌素^在剂量药物之后12小时:质量浓度:时间点:全血:定量型:
Synonyms: >12Hr之后于一剂药物 >12Hr之后于剂量药物 >12小时之后于一剂药物 >12小时之后于剂量药物 12Hr之后于一剂药物;12Hr之后于剂量药物;12小时之后于一剂药物;12小时之后于剂量药物;在一剂药物之后12Hr;在一剂药物之后12小时;在剂量药物之后12Hr XXX刺激 - 在...之后 一剂物质 一剂药物 之后于... 之后于剂量物质;之后于剂量药物;在剂量物质之后 剂量物质 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 在...以后 在一剂药物之后>12Hr 在一剂药物之后>12小时 在一剂药物之后大于12Hr 在一剂药物之后大于12小时 在剂量药物之后>12Hr 在剂量药物之后>12小时 在剂量药物之后大于12Hr 在后 大于12Hr之后于一剂药物 大于12Hr之后于剂量药物 大于12小时之后于一剂药物 大于12小时之后于剂量药物 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 环孢霉素A; 山地明环孢灵; 环孢多肽A; 环孢素; 赛斯平; 环孢菌素; 环孢菌素A; 环孢素A;山地明;环孢多肽;环孢抑制剂;环孢灵;环孢霉素;环孢霉素A;环孢素;Cyclosporine;Cyclosporin; Restasis; Cyclosporine A; cyclosporin A; Antibiotic S 7481F1; 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonameth 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

Unit Source
ng/mL REGENSTRIEF
ug/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=3523-8