Urate [Mass or Moles/volume] in 24 hour Urine
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Uric acid (urate) is a product of the metabolic breakdown of purine nucleotides. In humans, about 70% of daily uric acid disposal occurs via the kidneys.
Elevated levels of uric acid, or hyperuricemia, may be due to genetic inheritance or diet. Excess serum levels of uric acid can lead to a type of arthritis known as gout, kidney stones, cardiovascular disease, Type 2 diabetes, and metabolic syndrome. Lesch-Nyhan syndrome (LNS), an extremely rare inherited disorder, is also associated with very high serum uric acid levels. Spasticity, involuntary movement and cognitive retardation as well as manifestations of gout are seen in cases of this syndrome. LNS is due to mutations in the HPRT1 gene. To date (2012), mutations in nine other genes have been linked to the excretion of uric acid by the kidneys: SLC2A9; ABCG2; SLC17A1; SLC22A11; SLC22A12; SLC16A9; GCKR; LRRC16A; and PDZK1.
Decreased levels of uric acid, known as hypouricemia, can have numerous causes, including low dietary zinc or iron intake. Hypouricemia has been associated with multiple sclerosis (MS). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Urate (Wikipedia)
- Short Name
- Urate 24h Ur-msCnc
- Display Name
- Urate (24H U) [Mass or moles/Vol]
- Consumer Name Alpha
- Urate, Urine
- First Released
- Version 2.11
- Last Updated
- Version 2.42
- Order vs. Observation
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