3535-2
Desipramine [Mass/volume] in Serum or Plasma --trough
Active
Part Descriptions
LP16103-1 Desipramine
Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. It is sold under the brand names Norpramin ® and Pertofrane ®. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. Desipramine is an active metabolite of imipramine. Along with other tricyclics, desipramine has found use in treating neuropathic pain. The mechanism of action seems to involve the activation, through norepinephrine reuptake inhibition, of descending pathways in the spinal cord that block pain signals from ascending to the brain. Desipramine is one of the most potent and selective medications in this respect. Some evidence suggests that desipramine may help with ADD. See also:antidepressant tricyclic antidepressant External links:Desipramine - medicinenet.comDesipramine - medlineplus.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Desipramine (Wikipedia)
LP16103-1 Desipramine
A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
Source: National Library of Medicine, MeSH 2006
LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Trough levels for therapeutic drug monitoring
LOINC Names Get Info
- Fully-Specified Name
- Desipramine^trough:
MCnc: Pt: Ser/Plas: Qn: - Long Common Name
- Desipramine [Mass/volume] in Serum or Plasma --trough
- Short Name
- Desipramine Trough SerPl-mCnc
- Display Name
- Desipramine trough [Mass/Vol]
- Consumer Name Alpha Get Info
- Desipramine trough, Blood
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.40 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Desipramin^Údolní koncentrace: |
| el-GR | Greek (Greece) | Δεσιπραμίνη^ελάχιστα επίπεδα: Synonyms: DRUG/TOX MCnc Pt Qn Δεσιπραμίνη ελάχιστα επίπεδα Ορός Ορός/Πλάσμα Πλάσμα |
| es-AR | Spanish (Argentina) | desipramina^concentración mínima [valle]: |
| es-ES | Spanish (Spain) | Desipramina^Valle monitorización terapéutica de fármacos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Desipramina ^ canal: |
| et-EE | Estonian (Estonia) | Desipramiin^baas: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Désipramine^Creux: |
| fr-FR | French (France) | Désipramine^taux résiduel: |
| fr-BE | French (Belgium) | Désipramine^Creux: Synonyms: Minimum, nadir |
| it-IT | Italian (Italy) | Desipramina^valore minimo: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM |
| ko-KR | Korean (Korea, Republic Of) | 데시프라민^최저 약물 농도 시간: |
| nl-NL | Dutch (Netherlands) | desipramine^dalspiegel: |
| pt-BR | Portuguese (Brazil) | Desipramina^basal: Synonyms: Imipramine metAcolite; |
| ru-RU | Russian (Russian Federation) | Дезипрамин^остаточная концентрация: Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Desipramin^en düşük: Synonyms: çukur düzey |
| zh-CN | Chinese (China) | 去甲丙咪嗪^波谷: Synonyms: C18H22N2; |
Example Units
| Unit | Source |
|---|---|
| ng/mL | Example UCUM Units |
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