Version 2.80

Part Description

LP16112-2   Dicoumarol
Dicoumarol (International Nonproprietary Name) or dicumarol (United States Adopted Name) is an anticoagulant that functions as a Vitamin K antagonist (similar to warfarin, for which it was the inspiration). It is also used in biochemical experiments as an inhibitor of reductases.

Dicoumarol is a natural chemical substance of combinded plant and fungal origin. It is a derivative of coumarin, a substance made by plants that does not itself affect coagulation, but which is (classically) transformed in mouldy feeds by a number of species of fungi into active dicoumarol. Dicoumarol does affect coagulation, and was discovered in mouldy wet sweet-clover hay, as the agent of a naturally occurring bleeding disease in cattle.

It is given only orally, and it acts within two days.

Mechanism of action : it is a competitive inhibitor of Vitamin K preventing the formation of prothrombin. Administration of Vitamin K is the antidote for dicoumarol toxicity. Follow-up is done by measuring the prothrombin time (PT).

Uses: Used along with heparin for the treatment of deep venous thrombosis Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

Fully-Specified Name

Component
Dicoumarol
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Dicoumarol [Mass/volume] in Serum or Plasma
Short Name
Dicoumarol SerPl-mCnc
Display Name
Dicoumarol [Mass/Vol]
Consumer Name Alpha Get Info
Dicoumarol, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.34 (MIN)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Δικουμαρόλη:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: MCnc Δικουμαρόλη
es-AR Spanish (Argentina) dicumarol:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Dicumarol:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Dicumarol:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Dikumarool:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Dicoumarol:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Dicoumarol:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Dicoumarol:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Dicoumarol:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 디쿠마롤:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) dicoumarol:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Dicumarol:MCnc:Pt:Sor/Plas:Qn:
Synonyms: Dicoumarin; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Дикумарол:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Dikumarol:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 双香豆素:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 双杀鼠灵;双羟香豆素;抗血凝性杀鼠剂;紫苜蓿酚;败坏翘摇素 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

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