35668-3
Gentamicin [Mass/volume] in Serum or Plasma
Active
Part Description
LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275]
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | Use this code for random Gentamicin tests (it is equivalent). Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Fully-Specified Name
- Component
- Gentamicin
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Gentamicin SerPl-mCnc
- Display Name
- Gentamicin [Mass/Vol]
- Consumer Name Alpha Get Info
- Gentamicin, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.13
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 2321
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG43842-0 | Gentamicin| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Gentamicin: |
| de-AT | German (Austria) | Synonyms: Gentamycin |
| el-GR | Greek (Greece) | Γενταμυκίνη: |
| es-MX | Spanish (Mexico) | Gentamicina: |
| es-ES | Spanish (Spain) | Gentamicina: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | gentamicina.alta potencia: |
| et-EE | Estonian (Estonia) | Gentamütsiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Gentamicine: |
| fr-FR | French (France) | Gentamicine: |
| fr-BE | French (Belgium) | Gentamicine: |
| it-IT | Italian (Italy) | Gentamicina: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 겐타마이신: |
| nl-NL | Dutch (Netherlands) | gentamicine: |
| pt-BR | Portuguese (Brazil) | Gentamicina: Synonyms: c213; |
| ru-RU | Russian (Russian Federation) | Гентамицин: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Gentamisin: |
| uk-UA | Ukrainian (Ukraine) | Гентаміцин: Synonyms: Aminoglycosides; |
| zh-CN | Chinese (China) | 庆大霉素: Synonyms: 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| mcg/mL | REGENSTRIEF |
| mg/L | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=35668-3
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