Version 2.80

Part Description

LP15747-6   Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

Fully-Specified Name

Component
Gentamicin^peak
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Gentamicin [Mass/volume] in Serum or Plasma --peak
Short Name
Gentamicin Peak SerPl-mCnc
Display Name
Gentamicin peak [Mass/Vol]
Consumer Name Alpha Get Info
Gentamicin Peak, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
3303

Member of these Groups Get Info

LOINC Group Group Name
LG50393-4 Gentamicin^peak|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Gentamicin^TDM Spitze:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
de-AT German (Austria) Synonyms: Gentamycin (PEAK)
el-GR Greek (Greece) Γενταμυκίνη^μέγιστη:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: MCnc Γενταμυκίνη
es-MX Spanish (Mexico) Gentamicina ^ pico:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ES Spanish (Spain) Gentamicina^Pico monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-AR Spanish (Argentina) gentamicina^pico:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
et-EE Estonian (Estonia) Gentamütsiin^tipp:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Gentamicine^Pic:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Gentamicine pic:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Gentamicine^Pic:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Gentamicina^picco:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Picco TDM Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 겐타마이신^최고 약물 농도 시간:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) gentamicine^piek:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Gentamicina^pico:MCnc:Pt:Sor/Plas:Qn:
Synonyms: c213; Gent; Garamycin; Genj; Genirr; Post; Post-dose; Postdose; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Гентамицин^пик:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Gentamisin^tepe:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 庆大霉素^波峰:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 一剂药物的后剂量(Postdose);剂量药物的后剂量(Postdose);后剂量(Postdose);峰值;曲线上的最大值;最高点;治疗药物监测 - 波峰 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 正泰霉素;艮他霉素 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
mcg/mL REGENSTRIEF
mg/L Example UCUM Units
mg/L eCHN

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=3663-2