Version 2.78

Part Description

LP115359-4   Chlamydia trachomatis & Neisseria gonorrhoeae
Target amplification assays are based on the ability of complementary oligonucleotide primers to specifically anneal and allow enzymatic amplification of the target nucleic acid strands. The GEN-PROBE APTIMA Combo 2 Assay replicates a specific region of the 23S rRNA from CT and a specific region of the 16S rRNA from GC via DNA intermediates. A unique set of primers is used for each target molecule. Detection of the rRNA amplification product sequences (amplicon) is achieved using nucleic acid hybridization. Single-stranded chemiluminescent DNA probes, which are complementary to a region of each target amplicon, are labeled with different acridinium ester molecules. The labeled DNA probes combine with amplicon to form stable RNA:DNA hybrids. The Selection Reagent differentiates hybridized from unhybridized probe, eliminating the generation of signal from unhybridized probe. During the detection step, light emitted from the labeled RNA:DNA hybrids is measured as photon signals in a luminometer, and are reported as Relative Light Units (RLU). In DKA, differences in the kinetic profiles of the CT and GC labeled probes allow for the differentiation of signal; kinetic profiles are derived from measurements of photon output during the detection read time. The chemiluminescent detection reaction for CT signal has very rapid kinetics and has the "flasher" kinetic type. The chemiluminescent detection reaction for GC signal is relatively slower and has the "glower" kinetic type. Assay results are determined by a cut-off based on the total RLU and the kinetic curve type. Source: Regenstrief Help

Fully-Specified Name

Component
Chlamydia trachomatis & Neisseria gonorrhoeae DNA
Property
Prid
Time
Pt
System
XXX
Scale
Nom
Method
Probe.amp.tar

Additional Names

Short Name
C trach+GC DNA Spec NAA+probe
Display Name
C. trachomatis and N. gonorrhoeae DNA NAA+probe Nom (Specimen)
Consumer Name Alpha Get Info
Chlamydia trachomatis & Neisseria gonorrhoeae, Specimen

Example Answer List: LL1501-7

Source: Association of Public Health Laboratories
Answer Code Score Answer ID
Chlamydia trachomatis detected LA16153-1
Chlamydia trachomatis not detected LA16154-9
Chlamydia trachomatis inconclusive LA16155-6
Chlamydia trachomatis equivocal LA16157-2
Neisseria gonorrhoeae detected LA16150-7
Neisseria gonorrhoeae not detected LA16151-5
Neisseria gonorrhoeae inconclusive LA16152-3
Neisseria gonorrhoeae equivocal LA16156-4

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.13
Last Updated
Version 2.73
Change Reason
Changed + to & in Component because this is a Prid/Nom term that is used for assays that can detect and differentiate between the organisms.
Order vs. Observation
Both
Common Test Rank Get Info
2464

Member of these Panels

LOINC Long Common Name
86636-8 Family planning report - FPAR 2.0 set
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets
94137-7 HEDIS 2020 Value Sets
96068-2 HEDIS MY 2020 Value Sets

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Chlamydia trachomatis & Neisseria gonorrhoeae DNA:Nachweis oder Identität:Zeitpunkt:XXX:Nominal:Zielfragmentamplifikation mit Sondendetektion
es-AR Spanish (Argentina) [anticuerpo anti - ] Neisseria gonorrhoeae [Ac]:presencia o identidad:punto en el tiempo:XXX:Nominal:sonda.amplificación.blanco
es-ES Spanish (Spain) Chlamydia trachomatis & Neisseria gonorrhoeae ADN:Presencia o identidad:Punto temporal:XXX:Nom:Sonda con amplificación dirigida
es-MX Spanish (Mexico) ADN de Chlamydia trachomatis y Neisseria gonorrhoeae:Presencia o identidad:Punto temporal:XXX:Nominal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Chlamydia trachomatis & Neisseria gonorrhoeae, ADN:Présence ou identité:Temps ponctuel:XXX:Nominal:Sonde avec amplification de la cible
fr-FR French (France) Chlamydia trachomatis et Neisseria gonorrhoeae ADN:Identification:Ponctuel:Milieux divers:Résultat nominal:PCR amplification de cible
it-IT Italian (Italy) Chlamydia trachomatis & Neisseria gonorrhoeae DNA:Prid:Pt:XXX:Nom:Sonda.amp.tar
Synonyms: Chlamydia trachomatis e Neisseria gonorrhoeae Microbiologia Presenza o Identità Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
ko-KR Korean (Korea, Republic Of) 클라미디아 트라코마티스+임균 디옥시리보핵산:존재:검사시점:XXX:명칭결과:DNA 탐색자.증폭.표적
nl-NL Dutch (Netherlands) Chlamydia trachomatis & Neisseria gonorrhoeae DNA:identificator:moment:XXX:nominaal:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Chlamydia trachomatis+Neisseria gonorrhoeae DNA:Ident:Pt:XXX:Nom:Sonda com limite de detecção da amplificação de alvo
Synonyms: ; N gonorrhoea; N gonorrhoeae; Gono; GC; Gonorrhea; Deoxyribonucleic acid; C trach+GC; CT/GC; C trac; C trachomatis; Chlam trac; C trach; C tracho; CT; Trachoma; Lymphogranuloma venereum; LGV; Identity or presence; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Nominal; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Chlamid; Microbiology
ru-RU Russian (Russian Federation) Chlamydia trachomatis & Neisseria gonorrhoeae ДНК:ПрИд:ТчкВрм:XXX:Ном:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Номинальный;Именной Присутствие или Идентификация Проба с мишени усилением Точка во времени;Момент
uk-UA Ukrainian (Ukraine) Chlamydia trachomatis та Neisseria gonorrhoeae ДНК:Наявність або Ідентифікація:МоментЧасу:ХХХ:Категорійно:Зонд-детекція. цільова аміпліфікація НК
Synonyms: 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; C trac; C trach; C trach+GC; C tracho; C trachomatis; Chlam; Chlam trac; Chlamid; CT; CT + NG DNA; CT/GC; Deoxyribonucleic acid; DNA NUCLEIC ACID PROBE; DNA probe; GC; Gono; Gonorrhea; ID; Identity or presence; Infectious Disease; InfectiousDisease; LAT; LCR; LGV; Ligase chain reaction; Ligation-activated transcription; Lymphogranuloma venereum; Microbiology; Misc; Miscellaneous; N gonorrhoea; N gonorrhoeae; NAA+probe; NAAT; NASBA; Nominal; Nucleic acid sequence based analysis; Other; PCR; Point in time; Polymerase chain reaction; Probe amp; Probe with ampification; Probe with target amplification; QBR; Random; SDA; Spec; Strand Displacement Amplification; TMA; To be specified in another part of the message; Trachoma; Transcription mediated amplification; UniversalLabOrders; Unspecified
zh-CN Chinese (China) 沙眼衣原体与淋病奈瑟菌 DNA:存在与否或特征标识:时间点:XXX:名义型:探针法.基因扩增.靶向
Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 椒疮;沙眼;砂眼;粒性结膜炎;颗粒性结膜炎 沙眼衣原体+淋病奈瑟菌（淋球菌、淋病、淋病双球菌、淋病奈瑟氏菌）;C trach+GC;CT/GC 沙眼衣原体与淋病奈瑟菌（淋球菌、淋病、淋病双球菌、淋病奈瑟氏菌） 淋球菌 DNA 淋球菌;淋病;淋病双球菌;淋病奈瑟氏菌 淋病奈瑟氏菌 DNA 经过扩增的 脱氧核糖核酸探针 衣原体属

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=36903-3