36903-3

Chlamydia trachomatis and Neisseria gonorrhoeae DNA [Identifier] in Specimen by NAA with probe detection

Active

Part Description

LP115359-4   Chlamydia trachomatis & Neisseria gonorrhoeae
Target amplification assays are based on the ability of complementary oligonucleotide primers to specifically anneal and allow enzymatic amplification of the target nucleic acid strands. The GEN-PROBE APTIMA Combo 2 Assay replicates a specific region of the 23S rRNA from CT and a specific region of the 16S rRNA from GC via DNA intermediates. A unique set of primers is used for each target molecule. Detection of the rRNA amplification product sequences (amplicon) is achieved using nucleic acid hybridization. Single-stranded chemiluminescent DNA probes, which are complementary to a region of each target amplicon, are labeled with different acridinium ester molecules. The labeled DNA probes combine with amplicon to form stable RNA:DNA hybrids. The Selection Reagent differentiates hybridized from unhybridized probe, eliminating the generation of signal from unhybridized probe. During the detection step, light emitted from the labeled RNA:DNA hybrids is measured as photon signals in a luminometer, and are reported as Relative Light Units (RLU). In DKA, differences in the kinetic profiles of the CT and GC labeled probes allow for the differentiation of signal; kinetic profiles are derived from measurements of photon output during the detection read time. The chemiluminescent detection reaction for CT signal has very rapid kinetics and has the "flasher" kinetic type. The chemiluminescent detection reaction for GC signal is relatively slower and has the "glower" kinetic type. Assay results are determined by a cut-off based on the total RLU and the kinetic curve type. Source: Regenstrief Help

LOINC Names Get Info

Fully-Specified Name

Chlamydia trachomatis & Neisseria gonorrhoeae DNA:Prid:Pt:XXX:Nom:Probe.amp.tar

Long Common Name

Chlamydia trachomatis and Neisseria gonorrhoeae DNA [Identifier] in Specimen by NAA with probe detection

Short Name

C trach+GC DNA Spec NAA+probe

Display Name

C. trachomatis and N. gonorrhoeae DNA NAA+probe Nom (Specimen)

Consumer Name Alpha Get Info

Chlamydia trachomatis & Neisseria gonorrhoeae, Specimen

Part Model Get Info

• Component

  Chlamydia trachomatis & Neisseria gonorrhoeae DNA
  LP157729-7

  • Analyte

    Chlamydia trachomatis & Neisseria gonorrhoeae DNA
    LP157729-7

    • Component Numerator

      Chlamydia trachomatis & Neisseria gonorrhoeae DNA
      LP157729-7

      • Component Numerator Core

        Chlamydia trachomatis & Neisseria gonorrhoeae
        LP115359-4

      • Component Numerator Core Suffix

        DNA
        LP32416-7

    • Component Denominator

      NULL
       

      • Component Denominator Core

        NULL
         

      • Component Denominator Core Suffix

        NULL
         

  • Challenge

    NULL
     

  • Adjustment

    NULL
     

  • Count

    NULL
     

• Property

  Prid
  LP6850-4

• Time

  Pt
  LP6960-1

  • Time Core

    Pt
    LP6960-1

  • Time Modifier

    NULL
     

• System

  XXX
  LP7735-6

  • System Core

    XXX
    LP7735-6

  • Super System

    NULL
     

• Scale

  Nom
  LP7750-5

• Method

  Probe.amp.tar
  LP6464-4

Example Answer List: LL1501-7

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.13

Last Updated

Version 2.73 (MIN)

Change Reason

Changed + to & in Component because this is a Prid/Nom term that is used for assays that can detect and differentiate between the organisms.

Order vs. Observation

Both

Common Test Rank Get Info

2464

Member of these Panels

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• C trac
• C trach
• C trach+GC
• C tracho
• C trachomatis
• Chlam
• Chlam trac
• Chlamid
• CT
• CT + NG DNA
• CT/GC
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• GC
• Gono
• Gonorrhea
• ID
• Identity or presence
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• LGV
• Ligase chain reaction
• Ligation-activated transcription
• Lymphogranuloma venereum
• Microbiology
• Misc
• Miscellaneous
• N gonorrhoea
• N gonorrhoeae
• NAA+probe
• NAAT
• NASBA
• Nominal
• Nucleic acid sequence based analysis
• Other
• PCR
• Point in time
• Polymerase chain reaction
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• Random
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• To be specified in another part of the message
• Trachoma
• Transcription mediated amplification
• UniversalLabOrders
• Unspecified

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=36903-3

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.