374-9
Ofloxacin [Susceptibility] by Minimum lethal concentration (MLC)
Active
Part Descriptions
LP16182-5 Ofloxacin
Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. The original brand, Floxin, has been discontinued by the manufacturer in the United States in 2009, though generic equivalents continue to be available.
Oral and I.V. Floxin is not licensed by the FDA for use in children due to the risk of serious reversible and irreversible injury to the musculoskeletal system. Ofloxacin (and its derivatives) has also been associated with a few isolated reports of unexplained pediatric fatalities. Children (those under 18) are also at an increased risk of bone, joint, or tendon toxicities.
In the adult population ofloxacin is limited to the treatment of proven serious and life threatening bacterial infections such as:
Acute bacterial exacerbations of chronic bronchitis
Community-acquired pneumonia
Uncomplicated skin and skin structure infections
Nongonococcal urethritis and cervicitis
Mixed Infections of the urethra and cervix
Acute pelvic inflammatory disease
Uncomplicated cystitis
Complicated urinary tract infections
Prostatitis
Acute, uncomplicated urethral and cervical gonorrhea
Mycobacterial infections
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Source: Wikipedia, Ofloxacin (Wikipedia)
LP16182-5 Ofloxacin
A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Ofloxacin
- Property
- Susc
- Time
- Pt
- System
- Isolate
- Scale
- Qn
- Method
- MLC
Additional Names
- Short Name
- Ofloxacin Islt MLC
- Display Name
- Ofloxacin MLC [Susc]
- Consumer Name Alpha Get Info
- Susceptibility to Ofloxacin
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.19
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
87927-0 | Bacterial susceptibility panel - Isolate by Minimum lethal concentration (MLC) |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG41088-2 | OfloxacinSusc| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Ofloxacin: |
es-AR | Spanish (Argentina) | ofloxacina: |
es-ES | Spanish (Spain) | Ofloxacina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Ofloxacina: |
et-EE | Estonian (Estonia) | Ofloksatsiin: Synonyms: Isolaat Juhuslik Kvantitatiivne Minimaalne letaalne kontsentratsioon Tundlikkus |
fr-CA | French (Canada) | Ofloxacine: |
fr-FR | French (France) | Ofloxacine: |
fr-BE | French (Belgium) | Ofloxacine: |
it-IT | Italian (Italy) | Ofloxacina: Synonyms: Concentrazione minima letale (MLC) Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici |
ko-KR | Korean (Korea, Republic Of) | 오플록사신: |
nl-NL | Dutch (Netherlands) | ofloxacine: Synonyms: MLC |
pt-BR | Portuguese (Brazil) | Ofloxacina: Synonyms: Floxin; |
tr-TR | Turkish (Turkey) | Oflokzasin: |
zh-CN | Chinese (China) | 氧氟沙星: Synonyms: 分离物; |
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