LP16182-5
Ofloxacin
Active
Descriptions
Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. The original brand, Floxin, has been discontinued by the manufacturer in the United States in 2009, though generic equivalents continue to be available.
Oral and I.V. Floxin is not licensed by the FDA for use in children due to the risk of serious reversible and irreversible injury to the musculoskeletal system. Ofloxacin (and its derivatives) has also been associated with a few isolated reports of unexplained pediatric fatalities. Children (those under 18) are also at an increased risk of bone, joint, or tendon toxicities.
In the adult population ofloxacin is limited to the treatment of proven serious and life threatening bacterial infections such as:
Acute bacterial exacerbations of chronic bronchitis
Community-acquired pneumonia
Uncomplicated skin and skin structure infections
Nongonococcal urethritis and cervicitis
Mixed Infections of the urethra and cervix
Acute pelvic inflammatory disease
Uncomplicated cystitis
Complicated urinary tract infections
Prostatitis
Acute, uncomplicated urethral and cervical gonorrhea
Mycobacterial infections
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Source: Wikipedia, Ofloxacin (Wikipedia)
A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Display Name
- Ofloxacin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Ofloxacin
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 氧氟沙星 Synonyms: 吡啶羧酶 |
fr-CA | French (Canada) | Ofloxacine |
et-EE | Estonian (Estonia) | Ofloksatsiin |
es-ES | Spanish (Spain) | Ofloxacina |
it-IT | Italian (Italy) | Ofloxacina |
tr-TR | Turkish (Turkey) | Oflokzasin |
ru-RU | Russian (Russian Federation) | Офлоксацин |
nl-NL | Dutch (Netherlands) | ofloxacine |
fr-BE | French (Belgium) | Ofloxacine |
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