38381-0

Influenza virus A cDNA [Presence] in Specimen by NAA with probe detection

Active

Part Description

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name

Influenza virus A cDNA:PrThr:Pt:XXX:Ord:Probe.amp.tar

Long Common Name

Influenza virus A cDNA [Presence] in Specimen by NAA with probe detection

Short Name

FLUAV cDNA Spec Ql NAA+probe

Display Name

FLUAV cDNA NAA+probe Ql (Specimen)

Consumer Name Alpha Get Info

Influenza A (Flu A), Specimen

Part Model Get Info

• Component

  Influenza virus A cDNA
  LP174058-0

  • Analyte

    Influenza virus A cDNA
    LP174058-0

    • Component Numerator

      Influenza virus A cDNA
      LP174058-0

      • Component Numerator Core

        Influenza virus A
        LP14239-5

      • Component Numerator Core Suffix

        cDNA
        LP34188-0

    • Component Denominator

      NULL
       

      • Component Denominator Core

        NULL
         

      • Component Denominator Core Suffix

        NULL
         

  • Challenge

    NULL
     

  • Adjustment

    NULL
     

  • Count

    NULL
     

• Property

  PrThr
  LP217195-9

• Time

  Pt
  LP6960-1

  • Time Core

    Pt
    LP6960-1

  • Time Modifier

    NULL
     

• System

  XXX
  LP7735-6

  • System Core

    XXX
    LP7735-6

  • Super System

    NULL
     

• Scale

  Ord
  LP7751-3

• Method

  Probe.amp.tar
  LP6464-4

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.14

Last Updated

Version 2.73 (MIN)

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

5727

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Avian influenza
• Bird flu
• complementary DNA
• DNA NUCLEIC ACID PROBE
• DNA probe
• FLUA
• FLUAV
• FLUV
• Fowl plague
• ID
• Infectious Disease
• InfectiousDisease
• Influ
• Influenza A
• Influenza A virus
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Microbiology
• Misc
• Miscellaneous
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• Other
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Screen
• SDA
• Spec
• Strand Displacement Amplification
• TMA
• To be specified in another part of the message
• Transcription mediated amplification
• Unspecified

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.

CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=38381-0

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.