39082-3

Gentamicin [Mass/volume] in Cerebrospinal Fluid --peak

Active

Part Description

LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Gentamicin^peak:MCnc:Pt:CSF:Qn:
Long Common Name: Gentamicin [Mass/volume] in Cerebrospinal Fluid --peak
Short Name: Gentamicin Peak CSF-mCnc
Display Name: Gentamicin peak (CSF) [Mass/Vol]
Consumer Name Alpha Get Info: Gentamicin Peak, Spinal fluid

Part Model Get Info

Component
Gentamicin^peak
LP307916-9
- Analyte
  Gentamicin
  LP15747-6
  - Component Numerator
    Gentamicin
    LP15747-6
    - Component Numerator Core
      Gentamicin
      LP15747-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  peak
  LP20175-3
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
CSF
LP7156-5
- System Core
  CSF
  LP7156-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.15
Last Updated: Version 2.83 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gentamicin^Vrcholová koncentrace:Hmotnostní koncentrace:Časový bod:Mozkomíšní mok:Kvantitativní:
el-GR	Greek (Greece)	Γενταμυκίνη^μέγιστη:MCnc:Pt:ΕΝΥ:Qn: Synonyms: DRUG/TOX MCnc Pt Qn Γενταμυκίνη ΕΝΥ μέγιστη
es-ES	Spanish (Spain)	Gentamicina^Pico monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Líquido Cefalorraquideo:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Gentamicina ^ pico:Concentración de masa:Punto temporal:Fluído espinal cerebral:Cuantitativo:
et-EE	Estonian (Estonia)	Gentamütsiin^tipp:MCnc:Pt:CSF:Qn: Synonyms: Juhuslik Kvantitatiivne Liikvor
fr-CA	French (Canada)	Gentamicine^Pic:Concentration de masse:Temps ponctuel:LCR:Quantitatif:
fr-FR	French (France)	Gentamicine^pic:Masse/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
fr-BE	French (Belgium)	Gentamicine^Pic:Concentration de masse:Temps ponctuel:LCR:Quantitatif:
it-IT	Italian (Italy)	Gentamicina^picco:MCnc:Pt:LCS:Qn: Synonyms: Concentrazione di Massa Liquido cerebrospinale Livelli farmacologici e tossicologia Picco TDM Punto nel tempo (episodio)
ko-KR	Korean (Korea, Republic Of)	겐타마이신^최고 약물 농도 시간:질량농도:검사시점:뇌척수액:정량:
nl-NL	Dutch (Netherlands)	gentamicine^piek:massa/volume:moment:liquor cerebrospinalis:kwantitatief:
pt-BR	Portuguese (Brazil)	Gentamicina^pico:MCnc:Pt:LCR:Qn: Synonyms: c213; Gent; Garamycin; Genj; Genirr; Post; Post-dose; Postdose; Mass concentration; Level; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Гентамицин^пик:МассКонц:ТчкВрм:ЦСЖ:Колич: Synonyms: Количественный Массовая концентрация Точка во времени;Момент Цереброспинальная жидкость
tr-TR	Turkish (Turkey)	Gentamisin^tepe:KütlKons:Zmlı:BOS:Kant: Synonyms: pik
zh-CN	Chinese (China)	庆大霉素^波峰:质量浓度:时间点:脑脊液:定量型: Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液一剂药物的后剂量(Postdose);剂量药物的后剂量(Postdose);后剂量(Postdose);峰值;曲线上的最大值;最高点;治疗药物监测 - 波峰可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间正泰霉素;艮他霉素毒品毒品类水平;浓度;质量浓度(单位体积) 脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类

Example Units

Unit	Source
ug/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.