Version 2.74

Part Description

LP28423-9   West Nile virus
The West Nile Virus (WNV) is an arbovirus that was first identified in the West Nile District of Uganda in 1937. In the fall of 1999, the National Veterinary Services Laboratory (NVLS) isolated WNV in a dead crow in New York City.(http://www.who.int/mediacentre/factsheets/fs354/en/) Over the following ten years, WNV spread throughout the United States, Canada, Mexico and the Carribbean. WNV is usually transmitted through the bite of the Culex mosquito, but can also be spread in blood transfusions, organ transplants, breast milk, intrauterine exposure and laboratory-acquired infections. Birds are the preferred host of WNV, and the American robin is an important amplifier host since it develops enough virus in its serum to infect feeding mosquitoes. Though most infections with WNV are subclinical for humans, between 2005 and 2009 there were 12,975 people infected with WNV, of which 35% had severe cases of neuroinvasive disease and 496 people died. For individuals who are 70 years of age or older, infection with WNV has a 15-29% fatality rate. For infants and immunocompromised patients infected with WNV, the fatality rate is even higher. Diagnosis of WNV is based on clinical symptoms and antibody titers. The IgM antibody-capture enzyme-linked immunosorbent assay (MAC-ELISA) is the key method used to diagnosis WNV in clinical settings. Antibody titers to WNV NS5 are detectable long-term in vivo and can be used to distinguish past infection with WNV from current infection. RNA is usually undetectable in serum after 13.2 days, but on rare occasions, has been found in serum beyond 40 days. Treatment of infection with WNV is mostly supportive. There are no FDA-approved drugs or vaccines available.[PMID: 12089283][PMID: 23034323] Source: Regenstrief LOINC

Fully-Specified Name

Component
West Nile virus Ab.IgM
Property
ACnc
Time
Pt
System
CSF
Scale
Qn
Method
IA

Additional Names

Short Name
WNV IgM CSF IA-aCnc
Display Name
West Nile virus IgM IA Qn (CSF)
Consumer Name Alpha
West Nile virus IgM antibody, Spinal fluid

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.15
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank
5625

Member of these Groups

LOINC Group Group Name
LG32768-0 West Nile virus

Language Variants

Tag Language Translation
zh-CN Chinese (China) 西尼罗河病毒 抗体.IgM:任意型浓度:时间点:脑脊液:定量型:免疫测定法
Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 WNV Ab WNV Ab.IgM WNV 抗体 WNV 抗体.IgM WNV;西尼罗河热;西尼罗河热病毒 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 M 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液(Cerebral spinal fluid,CSF) 脑脊髓液 西尼罗河热病毒 Ab 西尼罗河热病毒 Ab.IgM 西尼罗河热病毒抗体 西尼罗河热病毒抗体.IgM 西尼罗河病毒 Ab 西尼罗河病毒 Ab.IgM 西尼罗河病毒 IgM
fr-CA French (Canada) Virus du Nil occidental , IgM:Concentration arbitraire:Temps ponctuel:LCR:Quantitatif:IA
pt-BR Portuguese (Brazil) Vírus do Nilo Ocidental Ac.IgM:ACnc:Pt:LCR:Qn:Imunoensaio
Synonyms: ; WNV; Immune globulin M; Immunoglobulin M; Arbitrary concentration; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
es-ES Spanish (Spain) Virus Nilo Occidental IgM:Concentración arbitraria:Punto temporal:Líquido Cefalorraquideo:Qn:IA
ko-KR Korean (Korea, Republic Of) 웨스트 나일 바이러스 항체.면역글로불린 M:임의농도:검사시점:뇌척수액:정량:효소면역측정법
it-IT Italian (Italy) Nilo occidentale, virus Ab.IgM:ACnc:Pt:LCS:Qn:IA
Synonyms: Anticorpi IgM anticorpo Concentrazione Arbitraria Immunoassay Liquido cerebrospinale Microbiologia Punto nel tempo (episodio) Virus del Nilo occidentale
fr-FR French (France) West Nile virus Ac IgM:Arbitraire/Volume:Ponctuel:Liquide céphalorachidien:Numérique:Immunoanalyse
tr-TR Turkish (Turkey) Batı Nil virüsü Ab.IgM:SçKons:Zmlı:BOS:Kant:İA
Synonyms: Ak Ak.IgM İmmünölçüm, immünoassay
ru-RU Russian (Russian Federation) Западный Нил вирус Ат.IgM:ПроизвКонц:ТчкВрм:ЦСЖ:Колич:IA
Synonyms: Антитело Количественный Произвольная концентрация Точка во времени;Момент Цереброспинальная жидкость
nl-NL Dutch (Netherlands) West-Nijlvirus As.IgM:eenheid/volume:moment:liquor cerebrospinalis:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
fr-BE French (Belgium) Virus du Nil occidental Anticorps. IgM:Concentration arbitraire:Temps ponctuel:LCR:Quantitatif:IA
Synonyms: Anticorps
de-DE German (Germany) West-Nil-Virus Ak.IgM:Arbiträre Konzentration:Zeitpunkt:Zerebrospinalflüssigkeit:Quantitativ:Immunoassay
es-MX Spanish (Mexico) Ab.IgM del virus del Nilo Occidental:Concentración arbitraria:Punto temporal:Fluído espinal cerebral:Cuantitativo:Inmunoensayo

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR®

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=39573-1