3979-2
Probenecid [Presence] in Urine
Active
Part Descriptions
LP16260-9 Probenecid
Probenecid is a uricosuric drug, primarily used in treating gout or hyperuricemia, that increases uric acid removal in the urine. Probenecid also decreases the renal excretion of some drugs. In one study, probenecid was shown to more than double a patient's exposure to oseltamivir (trade name Tamiflu), an antiviral drug used to combat influenza. This is significant because nations are currently stockpiling oseltamivir in anticipation of an influenza pandemic, and the drug is in short supply. During World War II, probenecid was used to extend limited supplies of penicillin, and is still currently used to increase antibiotic concentrations in serious infections. It has also found use as a masking agent by athletes attempting to get away with using performance enhancing drugs. In the kidneys it is filtered at the glomerulus, secreted in the proximal tubule and reabsorbed in the distal tubule. Probenecid's exact mechanism of action in the kidneys' nephrons is unknown.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Probenecid (Wikipedia)
LP16260-9 Probenecid
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Probenecid
- Property
- PrThr
- Time
- Pt
- System
- Urine
- Scale
- Ord
- Method
Additional Names
- Long Common Name
- Probenecid [Presence] in Urine
- Short Name
- Probenecid Ur Ql
- Display Name
- Probenecid Ql (U)
- Consumer Name Alpha Get Info
- Probenecid, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- The Property has been changed from ACnc to reflect the new model for ordinal terms where results are based on a cut-off value.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 14458
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Προβενεσίδη: Synonyms: PrThr Προβενεσίδη |
| es-AR | Spanish (Argentina) | probenecid: |
| es-ES | Spanish (Spain) | Probenecid: |
| es-MX | Spanish (Mexico) | Probenecid: |
| et-EE | Estonian (Estonia) | Probenetsiid: Synonyms: Järgarvuline Juhuslik Uriin |
| fr-CA | French (Canada) | Probénécide: |
| fr-FR | French (France) | Probénécide: |
| fr-BE | French (Belgium) | Probénécide: |
| it-IT | Italian (Italy) | Probenecid: Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) |
| ko-KR | Korean (Korea, Republic Of) | 프로베네시드: |
| nl-NL | Dutch (Netherlands) | probenecide: |
| pt-BR | Portuguese (Brazil) | Probenecida: Synonyms: Benemid; |
| ru-RU | Russian (Russian Federation) | Пробенецид: Synonyms: Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | Probenesid: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 丙磺舒: Synonyms: 二丙苯磺胺; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=3979-2
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://