39804-0
Lipoprotein associated phospholipase A2 [Mass/volume] in Serum or Plasma
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Part Description
LP35390-1 Lipoprotein associated phospholipase A2
Lipoprotein associated phospholipase A2 (Lp-PLA2) is an enzyme currently being evaluated to assist in risk factor assessment of cardiovascular disease. This biomarker was previously known as platelet-activating factor acetylhydrolase (PAF-AH) and has two biological functions. One function is that Lp-PLA2 inactivates an important proinflammatory mediator known as platelet-activating factor (PAF). The other function of Lp-PLA2 is that is oxidatively hydrolyzes modified polyunsaturated fatty acids resulting in the chemical compounds lysophosphatidylcholine (LysoPC) and oxidized nonesterified fatty acids (OxNEFA). OxNEFA has powerful monocyte chemotactic activity. LysoPC increase inflammatory mediators such as cytokines, adhesion molecules and the chemotactic mediator MCP-1. LpPLA2 is positively associated with coronary disease but does not improve cardiovascular risk assessment over the traditional biomarkers. LpPLA2 has been more useful for assessing patients with a borderline risk than traditional biomarkers. LpPLA2 has been especially helpful when used to measure cardiac risk on patients with metabolic syndrome or diabetes. There is some speculation that LpPLA2 may eventually be used to monitor treatment efficacy. Future risk assessments for coronary disease will likely include multiple combinations of cardiac risk markers. PMID: 17892360 RefID 23065
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Lipoprotein associated phospholipase A2
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Lipoprotein associated phospholipase A2 [Mass/volume] in Serum or Plasma
- Short Name
- Lp-PLA2 SerPl-mCnc
- Display Name
- Lipoprotein associated phospholipase A2 [Mass/Vol]
- Consumer Name Alpha Get Info
- Lipoprotein Associated Phospholipase A2, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.15
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4889
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Λιποπρωτεΐνική φωσφολιπάση A2: Synonyms: A2 MCnc Λιποπρωτεΐνη Λιποπρωτεΐνική φωσφολιπάση A2 Φωσφολιπάση |
es-ES | Spanish (Spain) | Lipoproteina asociada a fosfolipasa A2: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Fosfolipasa A2 asociada a lipoproteínas: |
fr-CA | French (Canada) | Phospholipase A2 associée aux lipoprotéines: |
fr-FR | French (France) | Lipoprotéine associée à la phospholipase A2: |
fr-BE | French (Belgium) | Phospholipase A2 associée aux lipoprotéines: |
it-IT | Italian (Italy) | Fosfolipasi A2 associata a lipoproteina: Synonyms: Chimica Concentrazione di Massa Lipoproteine Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 지질단백 관련 인지질효소 A2: |
nl-NL | Dutch (Netherlands) | lipoproteïne geassocieerd fosfolipase A2: |
pl-PL | Polish (Poland) | Fosfolipaza A2 związana z lipoproteina: |
pt-BR | Portuguese (Brazil) | Lipoproteína associada a fosfolipase A2: Synonyms: Rk203; |
ru-RU | Russian (Russian Federation) | Липопротеин ассоциированная фосфолипаза A2: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Lipoprotein ilişkili fosfolipaz A2: |
zh-CN | Chinese (China) | 脂蛋白相关磷脂酶 A2: Synonyms: A2 型 LP; |
Example Units
Unit | Source |
---|---|
ng/dL | REGENSTRIEF |
ng/mL | Example UCUM Units |
ng/mL | REGENSTRIEF |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=39804-0
LOINC Copyright
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