40548-0
Mononuclear cells atypical [#/volume] in Blood by Manual count
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Part Descriptions
LP35592-2 Mononuclear cells.atypical
A Peripheral Blood Mononuclear Cell (PBMC) is a blood cell having a round nucleus, such as a lymphocyte or a monocyte. These blood cells are a critical component in the immune system to fight infection and adapt to intruders. The lymphocyte population consists of T cells (CD4 and CD8 positive ~75%), B cells and NK cells (~25% combined).
These cells are often extracted from whole blood using ficoll, a hydrophilic polysaccharide that separates layers of blood, with monocytes and lymphocytes forming a buffy coat under a layer of plasma. This buffy coat contains the PBMCs. Additionally, PBMC can be extracted from whole blood using a hypotonic lysis which will preferentially lyse red blood cells. This method results in neutrophils and other polymorphonuclear (PMN) cells which are important in innate immune defense to be obtained.
PBMCs are widely used in research and clinical uses every day. HIV research uses them because PBMCs include CD4+ cells, the cells HIV infects.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Mononuclear cell
LP35592-2 Mononuclear cells.atypical
Atypical mononuclear cells are morphologically abnormal lymphocytes or monocytes that may appear in a blood after immunizations or surgery, during infections, or at the onset of autoimmune diseases. Findings include primitive nuclei with a diffuse chromatin pattern and nucleoli, lobulated nuclei, and hyper-basophilic cytoplasm. The cells vary greatly in size and shape. Large numbers of atypical mononuclear cells can be seen with viral infections, including infectious mononucleosis (Epstein-Barr virus), infectious hepatitis (Hepatitis A virus) and bronchitis (adenovirus). Smaller numbers of atypical lymphocytes are seen in many other viral infections and in some bacterial and protozoan infections.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Mononuclear cells.atypical
- Property
- NCnc
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
- Manual count
Additional Names
- Long Common Name
- Mononuclear cells atypical [#/volume] in Blood by Manual count
- Short Name
- Atypical Mononuc # Bld Manual
- Display Name
- Mononuclear cells atypical Manual cnt (Bld) [#/Vol]
- Consumer Name Alpha Get Info
- Mononuclear cells atypical, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.15
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 6877
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Μονοπύρηνα κύτταρα.άτυπα: Synonyms: NCnc Κύτταρα Μονοπύρηνα κύτταρα Μονοπύρηνα κύτταρα.άτυπα |
es-ES | Spanish (Spain) | Células mononucleares atípicas: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Células mononucleares atípicas: |
fr-CA | French (Canada) | Cellules mononucléaires.atypiques: |
fr-FR | French (France) | Cellules mononucléées atypiques: |
fr-BE | French (Belgium) | Cellules mononucléaires.atypiques: Synonyms: Cellules mononucléées |
it-IT | Italian (Italy) | Cellule mononucleari.atipiche: Synonyms: Cellule mononucleari atipiche Concentrazione Numerica Ematologia (coagulazione) conta differenziale Punto nel tempo (episodio) Sangue |
ko-KR | Korean (Korea, Republic Of) | 비정형단핵 세포: |
nl-NL | Dutch (Netherlands) | mononucleaire cellen.atypisch: Synonyms: handmatige methode handmatige telling |
pl-PL | Polish (Poland) | Mononuklearne komórki.atypowe: Synonyms: koncentracja Mononuklearne komórki Mononuklearne komórki atypowe |
pt-BR | Portuguese (Brazil) | Células mononucleares,atípicas: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Мононуклеарные клетки.атипичные: Synonyms: Количественный Количество в объеме Кровь Точка во времени; |
tr-TR | Turkish (Turkey) | Mononükleer hücreler.atipik: Synonyms: El ile |
zh-CN | Chinese (China) | 单个核细胞.异型: Synonyms: 不典型 不典型单个核细胞; |
Example Units
Unit | Source |
---|---|
10*3/uL | Example UCUM Units |
10^9/L | eCHN |
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