Version 2.78

Part Description

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Fully-Specified Name

Component
Valproate.free
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Valproate Free SerPl-mCnc
Display Name
Valproate Free [Mass/Vol]
Consumer Name Alpha Get Info
Free valproate, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Change Reason
Order_Obs: changed from 'observation' to 'both' to reflect that the LOINC code can also be used as an order code.
Order vs. Observation
Both
Common Test Rank Get Info
1810

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
57775-9 Valproate.free and Valproate panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG47174-4 Valproate.free|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) valproato.libre:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Valproico libre:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Valproato.libre:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Valproaat.vaba:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Valproate.libre:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Valproate libre:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Valproate.libre:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Valproato.libero:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Valproato Libero
ko-KR Korean (Korea, Republic Of) 유리벨프로에이트:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) valproaat.vrije:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Valproato.livre:MCnc:Pt:Sor/Plas:Qn:
Synonyms: Valproic acid; Depakene; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; FR; Non-protein bound; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Вальпроат.свободный:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Valproat.serb:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 2-丙基戊酸.游离型:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 2-丙基戊酸.游离;游离 2-丙基戊酸;游离型 2-丙基戊酸 2-丙基戊酸钠;C8H15NaO2;丙基戊酸;丙戊酸;VPA;Valproate;Valproic Acid 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 游离 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 非蛋白结合型 非蛋白质结合型

Example Units

Unit Source
mcg/mL REGENSTRIEF
ug/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=4087-3