41194-2

West Nile virus Ab [Units/volume] in Serum by Immunoassay

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Part Description

LP28423-9   West Nile virus
The West Nile Virus (WNV) is an arbovirus that was first identified in the West Nile District of Uganda in 1937. In the fall of 1999, the National Veterinary Services Laboratory (NVLS) isolated WNV in a dead crow in New York City.(http://www.who.int/mediacentre/factsheets/fs354/en/) Over the following ten years, WNV spread throughout the United States, Canada, Mexico and the Carribbean. WNV is usually transmitted through the bite of the Culex mosquito, but can also be spread in blood transfusions, organ transplants, breast milk, intrauterine exposure and laboratory-acquired infections. Birds are the preferred host of WNV, and the American robin is an important amplifier host since it develops enough virus in its serum to infect feeding mosquitoes. Though most infections with WNV are subclinical for humans, between 2005 and 2009 there were 12,975 people infected with WNV, of which 35% had severe cases of neuroinvasive disease and 496 people died. For individuals who are 70 years of age or older, infection with WNV has a 15-29% fatality rate. For infants and immunocompromised patients infected with WNV, the fatality rate is even higher. Diagnosis of WNV is based on clinical symptoms and antibody titers. The IgM antibody-capture enzyme-linked immunosorbent assay (MAC-ELISA) is the key method used to diagnosis WNV in clinical settings. Antibody titers to WNV NS5 are detectable long-term in vivo and can be used to distinguish past infection with WNV from current infection. RNA is usually undetectable in serum after 13.2 days, but on rare occasions, has been found in serum beyond 40 days. Treatment of infection with WNV is mostly supportive. There are no FDA-approved drugs or vaccines available. PMID: 12089283 PMID: 23034323 Source: Regenstrief LOINC

Fully-Specified Name

Component

West Nile virus Ab

Property

ACnc

Time

Pt

System

Ser

Scale

Qn

Method

IA

Additional Names

Short Name

WNV Ab Ser IA-aCnc

Display Name

West Nile virus Ab IA Qn (S)

Consumer Name Alpha Get Info

West Nile virus antibody, Blood

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.15

Last Updated

Version 2.73

Change Reason

The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

11670

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Arbitrary concentration
• Autoantibodies
• Autoantibody
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• IAA
• ID
• Infectious Disease
• InfectiousDisease
• MEIA
• Microbiology
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Serum
• SR
• SUDS
• WNV

Example Units

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CodeSystem lookup

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LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.