41463-1

Wuchereria bancrofti+Brugia malayi Ag [Presence] in Serum by Immunoassay

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Part Description

LP35808-2   Wuchereria bancrofti+Brugia malayi
Wuchereria bancrofti, Brugia malayi and Brugia timori are the three species of filaria that cause lymphatic filariasis in humans living in the tropics and sub-tropics. Infection is spread from person to person by mosquito bites. The adult worms live and reproduce in the human lymphatic system, creating millions of microscopic worms called microfilariae. When a person who is infected is bitten by a mosquito, the mosquito becomes infected, and the microfilariae mature inside the mosquito. When the mosquito bites another person, the larval worms are passed from the mosquito to the human and travel to the lymphatic system, where they grow into adult worms. Most people with lymphatic filariasis are asymptomatic, and a few develop lymphedema, primarily in the legs, but also in the arms, breasts, and genitals. People with lymphedema are more susceptible to bacterial infections of the skin and lymphatic system, which can lead to hardening and thickening of the skin, also known as elephantiasis.
Filarial infection can also cause tropical pulmonary eosinophilia syndrome. Lymphatic filariasis primarily develops in people who have gotten mosquito bites in an endemic area over an extended period of time. [https://www.cdc.gov/parasites/lymphaticfilariasis/] Studies have shown that different IgG isotypes may characterize different stages of infection. IgG1, IgG2 and IgG3 are most common in asymptomatic patients, while IgG4 is a marker of active infection. PMID: 28118850 In addition, larval antigens may have a stronger IgG1 response, followed by IgG2 and IgG3, while IgG4 is the most common isotype found in response to adult filaria. PMID: 9491413 Source: Regenstrief LOINC

Fully-Specified Name

Component

Wuchereria bancrofti+Brugia malayi Ag

Property

PrThr

Time

Pt

System

Ser

Scale

Ord

Method

IA

Additional Names

Short Name

W bancr+B malayi Ag Ser Ql IA

Display Name

W. bancrofti+Brugia malayi Ag IA Ql (S)

Consumer Name Alpha Get Info

Wuchereria bancrofti+Brugia malayi antigen, Blood

Example Answer List: LL360-9

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.16

Last Updated

Version 2.65

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016. Removed spaces between plus sign.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list

Order vs. Observation

Both

Language Variants Get Info

Related Names

• Antigen
• Antigens
• B malayi
• Bancroftian filariasis
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• Filariasis
• Human lymphatic filariasis
• IAA
• ID
• Infectious Disease
• InfectiousDisease
• MEIA
• Microbiology
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• Serum
• SR
• SUDS
• W bancr
• W bancr+B malayi
• W bancrofti
• Wucheria bancrofti

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CodeSystem lookup

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