LOINC
Version 2.67

41463-1Wuchereria bancrofti+Brugia malayi Ag [Presence] in Serum by ImmunoassayActive

Part Description

LP35808-2   Wuchereria bancrofti+Brugia malayi
Wuchereria bancrofti, Brugia malayi and Brugia timori are the three species of filaria that cause lymphatic filariasis in humans living in the tropics and sub-tropics. Infection is spread from person to person by mosquito bites. The adult worms live and reproduce in the human lymphatic system, creating millions of microscopic worms called microfilariae. When a person who is infected is bitten by a mosquito, the mosquito becomes infected, and the microfilariae mature inside the mosquito. When the mosquito bites another person, the larval worms are passed from the mosquito to the human and travel to the lymphatic system, where they grow into adult worms. Most people with lymphatic filariasis are asymptomatic, and a few develop lymphedema, primarily in the legs, but also in the arms, breasts, and genitals. People with lymphedema are more susceptible to bacterial infections of the skin and lymphatic system, which can lead to hardening and thickening of the skin, also known as elephantiasis.
Filarial infection can also cause tropical pulmonary eosinophilia syndrome. Lymphatic filariasis primarily develops in people who have gotten mosquito bites in an endemic area over an extended period of time. [https://www.cdc.gov/parasites/lymphaticfilariasis/] Studies have shown that different IgG isotypes may characterize different stages of infection. IgG1, IgG2 and IgG3 are most common in asymptomatic patients, while IgG4 is a marker of active infection. [PMID: 28118850] In addition, larval antigens may have a stronger IgG1 response, followed by IgG2 and IgG3, while IgG4 is the most common isotype found in response to adult filaria. [PMID: 9491413] Source: Regenstrief LOINC

Fully-Specified Name

Component
Wuchereria bancrofti+Brugia malayi Ag
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IA

Additional Names

Short Name
W bancr+B malayi Ag Ser Ql IA
Display Name
W. bancrofti+Brugia malayi Ag IA Ql (S)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.65
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016. Removed spaces between plus sign.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
班氏吴策线虫+马来布鲁线虫 抗原:存在情况或阈值:时间点:血清:序数型:免疫测定法
nl-NLDutch (NETHERLANDS)
Wuchereria bancrofti + Brugia malayi Ag:aanwezigheid:moment:serum:ordinaal:immunoassay
et-EEEstonian (ESTONIA)
Wuchereria bancrofti + Brugia malayi antigeen:PrThr:Pt:S:Ord:IA
fr-BEFrench (BELGIUM)
Wuchereria bancrofti + Brugia malayi Ag:PrThr:Temps ponctuel:Sérum:Ordinal:IA
fr-CAFrench (CANADA)
Wuchereria bancrofti+Brugia malayi , Ag:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FRFrench (FRANCE)
Wuchereria bancrofti + Brugia malayi Ag:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
it-ITItalian (ITALY)
Wuchereria bancrofti + Brugia malayi , Ag:PrThr:Pt:Siero:Ord:IA
ko-KRKorean (KOREA, REPUBLIC OF)
Wuchereria bancrofti + Brugia malayi Antigen:임의농도:검사시점:혈청:순위척도:효소면역측정법
pt-BRPortuguese (BRAZIL)
Wuchereria bancrofti + Brugia malayi Ag:ACnc:Pt:Soro:Ord:Imunoensaio
ru-RURussian (RUSSIAN FEDERATION)
Wuchereria bancrofti + Brugia malayi Аг:PrThr:ТчкВрм:Сыв:Пор:IA
es-ESSpanish (SPAIN)
Wuchereria bancrofti+Brugia malayi Antígeno:PrThr:Punto temporal:Suero:Ord:IA
tr-TRTurkish (TURKEY)
Wuchereria bancrofti + Brugia malayi Ag:MevcEşik:Zmlı:Ser:Srl:İA

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=41463-1