41626-3

Brucella sp DNA [Presence] in Specimen by NAA with probe detection

Active

Part Descriptions

LP14160-3   Brucella sp
Brucella are gram-negative coccobacilli that commonly infect cows (Brucella abortus), pigs (Brucella suis), goats (Brucella melitensis), and dogs (Brucella canis), along with wild animals such as deer, elk, and moose. The main pathogenic species of Brucella are Brucella melitensis, Brucella suis and Brucella abortus. Brucella melitensis is a gram-negative coccobacillus bacterium from the Brucellaceae family. It mainly affects the reproductive tract of goats and sheep, and in some regions is the major cause of abortion in them. It can also negatively impact fertility and lactation over time. B. melitensis has the broadest host range, infecting cattle, camels and dogs, in addition to sheep, goats and humans. Brucella suis infections in pigs causes chronic inflammatory lesions in the reproductive organs or orchitis and may affect joints and/or other organs. Similar to B. melitensis, B. suis can cause abortion in pregnant hosts. Other impacts of the disease are sterility, posterior paralysis and spondylitis. It is transmitted mainly by ingestion of infected tissues or fluids. It can cause undulant fever. B. suis are gram-negative, facultative intracellular coccobacilli and can specifically produce in phagocytic cells. They are also non-spore-forming, non-capsulated, and non-motile. Brucella suis are differentiated into five strains. Strains 1-3 infect boars and pigs. Strain 2 has been found in wild boars but without signs of infection while they do infect pigs and hares. Brucella abortus is a species of the genus Brucella. Natural hosts of B. abortus are cattle and other bovidae. Abortion and placentitis are common effects on the pregnant animal.

When humans come in contact with an infected animal or animal products that are contaminated with Brucella, brucellosis may result. Most human infections are occupational. Over 70 percent of reported cases of brucellosis occur in the meat-processing and livestock industries. Infection is generally via skin wounds, but the organisms can also be inhaled. A common route of Brucella infection is eating or drinking infected dairy products that have not been pasteurized. Human infections are caused most frequently by B. melitensis, B. suis, and B. abortus, while B. canis causes only rare infections. B. melitensis is the most virulent. People infected with B. melitensis can suffer serious complications, including infection and inflammation of the bones and joints, and occasionally, the heart and brain. About 100-200 cases of brucellosis occur every year in the United States. Incubation period is one to three weeks, and flu like symptoms appear in the infected person, such as fever, sweats, headache, back pain, and weakness. Severe complications such as CNS infections or infections in the heart lining occur in about 5 percent of cases. Chronic symptoms like recurrent fever, arthritis, and fatigue may occur up to one year from illness onset. Information from ARUP laboratories.

Brucellosis plays an important role in the economy and health of many developing countries because of its impact on both livestock and humans. Source: Regenstrief LOINC

LP20003-7   Brucella
A genus of gram-negative, aerobic bacteria that causes BRUCELLOSIS. Its cells are nonmotile coccobacilli and are animal parasites and pathogens. The bacterium is transmissible to humans through contact with infected dairy products or tissue. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component

Brucella sp DNA

Property

PrThr

Time

Pt

System

XXX

Scale

Ord

Method

Probe.amp.tar

Additional Names

Short Name

Brucella DNA Spec Ql NAA+probe

Display Name

Brucella sp DNA NAA+probe Ql (Specimen)

Consumer Name Alpha Get Info

Brucella sp, Specimen

Example Answer List: LL360-9

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.16

Last Updated

Version 2.73

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list

Order vs. Observation

Both

Common Test Rank Get Info

16199

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Bruc
• Brucellosis
• Deoxyribonucleic acid
• DNA NUCLEIC ACID PROBE
• DNA probe
• ID
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Microbiology
• Misc
• Miscellaneous
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• Other
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Screen
• SDA
• Spec
• species
• spp
• Strand Displacement Amplification
• TMA
• To be specified in another part of the message
• Transcription mediated amplification
• Unspecified

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.

CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=41626-3

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.