42250-1

Variant lymphocytes/Leukocytes in Blood by Automated count

Active

Term Description

CLSI (formerly NCCLS) document "Reference Leukocyte Differential Count (Proportional) and Evaluation of Instrumental Methods", 1992, recommend the use of variant lymphocytes rather than atypical or reactive lymphocytes.

Part Descriptions

LP15072-9   Lymphocytes.variant
Variant lymphocytes (also called reactive or atypical) are a type of abnormal lymphocyte found in the peripheral blood. They can be a marker for certain viral illnesses, including infectious mononucleosis, viral hepatitis, CMV, HIV, and rubella, and can also occur as part of a drug reaction to drugs such as phenytoin and para-aminosalicylic acid. [NCBI Books: NBK263] Source: Regenstrief LOINC, NCBI Books: NBK263

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name

Lymphocytes.variant/Leukocytes:NFr:Pt:Bld:Qn:Automated count

Long Common Name

Variant lymphocytes/Leukocytes in Blood by Automated count

Short Name

Variant Lymphs NFr Bld Auto

Display Name

Variant lymphocytes/Leukocytes Auto (Bld)

Consumer Name Alpha Get Info

Variant lymphocytes/White Blood Cells, Blood

Part Model Get Info

• Component

  Lymphocytes.variant/leukocytes
  LP286446-2

  • Analyte

    Lymphocytes.variant/leukocytes
    LP286446-2

    • Component Numerator

      Lymphocytes.variant
      LP15072-9

      • Component Numerator Core

        Lymphocytes.variant
        LP15072-9

      • Component Numerator Core Suffix

        NULL
         

    • Component Denominator

      Leukocytes
      LP157588-7

      • Component Denominator Core

        Leukocytes
        LP157588-7

      • Component Denominator Core Suffix

        NULL
         

  • Challenge

    NULL
     

  • Adjustment

    NULL
     

  • Count

    NULL
     

• Property

  NFr
  LP6838-9

• Time

  Pt
  LP6960-1

  • Time Core

    Pt
    LP6960-1

  • Time Modifier

    NULL
     

• System

  Bld
  LP7057-5

  • System Core

    Bld
    LP7057-5

  • Super System

    NULL
     

• Scale

  Qn
  LP7753-9

• Method

  Automated count
  LP6141-8

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 2.16

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

Common Test Rank Get Info

8879

Member of these Panels

Language Variants Get Info

Related Names

• Atypical lymphocytes
• Auto
• Automated detection
• Blood
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Lymp
• Lymph
• Lympho
• Lymphocyte
• Lymphs
• Lymphs%
• Number fraction
• Percent
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Reactive lymphocytes
• Variant lymphocytes
• Variant Lymphs
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=42250-1

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.