42354-1
Tigecycline [Susceptibility] by Gradient strip
Active
Part Descriptions
LP36048-4 Tigecycline
Tiglylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine Tiglylglycine is an intermediate product of the catabolism of isoleucine. An elevated level of tiglylglycine is identified in urine of patients with beta-ketothiolase deficiency or with disorders of propionate metabolism PMID: 7923765.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
Tiglylglycine
LP36048-4 Tigecycline
Tigecycline (INN) is a glycylcycline antibiotic marketed under the brand name Tygacil. It was given a U.S. Food and Drug Administration (FDA) fast-track approval and was approved on June 17, 2005. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus and Acinetobacter baumannii. The New Delhi metallo-β-Lactamase multidrug-resistant Enterobacteriaceae has also shown susceptibility to tigecycline.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Wikipedia
LP6300-0 Gradient strip
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Tigecycline:
Susc: Pt: Isolate: OrdQn: Gradient strip - Long Common Name
- Tigecycline [Susceptibility] by Gradient strip
- Short Name
- Tigecycline Islt Grad strip
- Display Name
- Tigecycline Strip [Susc]
- Consumer Name Alpha Get Info
- Susceptibility to Tigecycline
Part Model Get Info
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.16
- Last Updated
- Version 2.56 (MIN)
- Change Reason
- Feb 2016-removed "E-test" from the short and long names because the "ETEST" name is trademarked
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 49589-5 | Bacterial susceptibility panel by Gradient strip |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG41299-5 | TigecyclineSusc| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Tigecyklin: |
| de-DE | German (Germany) | Tigecyclin: |
| el-GR | Greek (Greece) | Τιγεκυκλίνη: Synonyms: ABXBACT OrdQn Pt Susc Απομονωμένο στέλεχος Λωρίδα με διαβαθμίσεις Τιγεκυκλίνη |
| es-ES | Spanish (Spain) | Tigeciclina: |
| es-MX | Spanish (Mexico) | Tigeciclina: |
| et-EE | Estonian (Estonia) | Tigetsükliin: Synonyms: Isolaat Juhuslik Tundlikkus |
| fr-CA | French (Canada) | Tigécycline: |
| fr-FR | French (France) | Tigécycline: |
| fr-BE | French (Belgium) | Tigécycline: Synonyms: Tigette graduée |
| it-IT | Italian (Italy) | Tigeciclina: Synonyms: Gradiente striscia (E-test) Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici |
| ko-KR | Korean (Korea, Republic Of) | Tigecycline: |
| nl-NL | Dutch (Netherlands) | tigecycline: |
| pl-PL | Polish (Poland) | Tygecyklina: Synonyms: wrażliwość (mikroorganizmów) |
| pt-BR | Portuguese (Brazil) | Tigeciclina: Synonyms: Tygecycline; |
| ru-RU | Russian (Russian Federation) | Тайгециклин: Synonyms: Градиентная полоска (Е-тест) Порядковый или Количественный Точка во времени; |
| tr-TR | Turkish (Turkey) | Tigesiklin: |
| zh-CN | Chinese (China) | 替加环素: Synonyms: E-胶条法; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://