Version 2.77

Part Descriptions

LP36048-4   Tigecycline
Tiglylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine Tiglylglycine is an intermediate product of the catabolism of isoleucine. An elevated level of tiglylglycine is identified in urine of patients with beta-ketothiolase deficiency or with disorders of propionate metabolism PMID: 7923765. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Tiglylglycine

LP36048-4   Tigecycline
Tigecycline (INN) is a glycylcycline antibiotic marketed under the brand name Tygacil. It was given a U.S. Food and Drug Administration (FDA) fast-track approval and was approved on June 17, 2005. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus and Acinetobacter baumannii. The New Delhi metallo-β-Lactamase multidrug-resistant Enterobacteriaceae has also shown susceptibility to tigecycline. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP6300-0   Gradient strip
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component
Tigecycline
Property
Susc
Time
Pt
System
Isolate
Scale
OrdQn
Method
Gradient strip

Additional Names

Short Name
Tigecycline Islt Grad strip
Display Name
Tigecycline Strip [Susc]
Consumer Name Alpha Get Info
Susceptibility to Tigecycline

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.56
Change Reason
Feb 2016-removed "E-test" from the short and long names because the "ETEST" name is trademarked
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
49589-5 Bacterial susceptibility panel by Gradient strip

Member of these Groups Get Info

LOINC Group Group Name
LG41299-5 TigecyclineSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Tigecyclin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Gradientenstreifen
es-ES Spanish (Spain) Tigeciclina:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Tira de gradiente (E-prueba)
es-MX Spanish (Mexico) Tigeciclina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Tira de degradado
et-EE Estonian (Estonia) Tigetsükliin:Susc:Pt:Is:OrdQn:E-test
Synonyms: Isolaat Juhuslik Tundlikkus
fr-CA French (Canada) Tigécycline:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Bâtonnet gradué
fr-FR French (France) Tigécycline:Sensibilité:Ponctuel:Isolat:Alphanumérique:Bandelette graduée
fr-BE French (Belgium) Tigécycline:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Bâtonnet gradué
Synonyms: Tigette graduée
it-IT Italian (Italy) Tigeciclina:Susc:Pt:Isolato:OrdQn:Gradiente striscia
Synonyms: Gradiente striscia (E-test) Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
ko-KR Korean (Korea, Republic Of) Tigecycline:감수성:검사시점:분리주:정량 or 순위척도:그래디언 띠
nl-NL Dutch (Netherlands) tigecycline:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:gradiëntstrip
pt-BR Portuguese (Brazil) Tigeciclina:Susc:Pt:Isolado:OrdQn:Fitas gradiente
Synonyms: Tygecycline; Tygacil; Susceptibility; Susceptibilty; Sus; Suscept; Susceptibilities; Point in time; Random; Islt; Isol; E-test; E-strip; Etest; Estrip; E-test; ANTIBIOTIC SUSCEPTIBILITIES
ru-RU Russian (Russian Federation) Тайгециклин:Чув:ТчкВрм:Изолят:ПорКол:Градиентная полоска
Synonyms: Градиентная полоска (Е-тест) Порядковый или Количественный Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Tigesiklin:Duyr:Zmlı:İzolat:SrlKant:Gradiyent çubuğu
zh-CN Chinese (China) 替加环素:抗生素敏感性:时间点:分离株:定量型或序数型:梯度胶条法
Synonyms: E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条 分离物;分离菌;分离菌株;隔离种群 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 替格环素

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=42354-1