Version 2.78

Part Description

LP36232-4   MYC gene
The MYC gene (v-myc avian myelocytomatosis viral oncogene homolog) [HGNC Gene ID:7553] is located on chromosome 8q24.21. The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:4609] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component
MYC gene targeted mutation analysis
Property
Prid
Time
Pt
System
Bld/Tiss
Scale
Nom
Method
Molgen

Additional Names

Short Name
MYC gene Mut Anl Bld/T
Display Name
MYC gene targeted mutation analysis Molgen Nom (Bld/Tiss)
Consumer Name Alpha Get Info
MYC gene targeted mutation analysis, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.MUT
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.73
Change Reason
Based on LOINC Committee review (June 2016), "targeted" was added to the Component to clarify that this test is looking for a specific set of mutations as described in the LOINC User Guide under the Molecular Genetics section.
Order vs. Observation
Both
Common Test Rank Get Info
14027

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Gen MYC Analisis de mutaciones:Presencia o identidad:Punto temporal:Sangre o tejido:Nom:Genética molecular
es-MX Spanish (Mexico) Análisis de mutaciones dirigidas al gen MYC:Presencia o identidad:Punto temporal:Sangre o tejido:Nominal:Genética molecular
fr-FR French (France) MYC gène mutation cible trouvée:Identification:Ponctuel:Sang/Tissu:Résultat nominal:Biologie moléculaire
it-IT Italian (Italy) MYC, gene analisi di mutazione mirata:Prid:Pt:Sangue/Tess:Nom:Molgen
Synonyms: Gene MYC Genetica molecolare Mutazione genica Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
ko-KR Korean (Korea, Republic Of) MYC 유전자 돌연변이 분석:존재:검사시점:전혈/조직:명칭결과:분자유전
nl-NL Dutch (Netherlands) MYC-gen doelgerichte mutatie-analyse:identificator:moment:bloed of weefsel:nominaal:moleculair genetisch onderzoek
Synonyms: molgen MYC gen targeted
pt-BR Portuguese (Brazil) MYC análise de mutação genética:Ident:Pt:Sg/Tecido:Nom:Genética molecular
Synonyms: Identity or presence; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Nominal; PCR; Molecular genetics; Mut Anal; Burkitt lymphoma; Protooncogene homologous to myelocytomatosis virus; Burkitts lymphoma; v-myc myelocytomatosis viral oncogene homolog; c-MYC; Mutations; MOLPATH.MUTATIONS; MOLPATH.MUTATIONS; Molecular pathology
ru-RU Russian (Russian Federation) MYC ген исследование на мутацию:ПрИд:ТчкВрм:Кр/Тк:Ном:МолГен
Synonyms: Кровь Кровь или Ткань Номинальный;Именной Присутствие или Идентификация Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) MYC geni Mutasyon analizi:MevcKimlik:Zmlı:Kan/Dk:Snf:Molgen
zh-CN Chinese (China) MYC 基因 突变分析:存在与否或特征标识:时间点:全血/组织:名义型:分子遗传学类实验室方法
Synonyms: Burkitt 淋巴瘤 Burkitts 淋巴瘤 c-MYC MYC 原癌基因 v-myc myelocytomatosis viral oncogene homolog (avian);MYC;MRTL;bHLHe39;c-Myc;avian myelocytomatosis viral oncogene homolog;class E basic helix-loop-helix protein 39;myc proto-oncogene protein;myc-related translation/localization regulatory factor;proto-on v-myc 骨髓细胞瘤病毒原癌基因同源基因 v-myc 骨髓细胞瘤病毒原癌基因同源基因（v-myc myelocytomatosis viral oncogene homolog） v-myc 髓细胞瘤病毒原癌基因同源基因 v-myc 髓细胞组织增生病毒原癌基因同源基因 v-myc 髓细胞组织增生症病毒原癌基因同源基因 与骨髓细胞瘤病毒同源的原癌基因 与骨髓细胞瘤病毒同源的原癌基因（Protooncogene homologous to myelocytomatosis virus） 与髓细胞瘤病毒同源的原癌基因 与髓细胞组织增生病毒同源的原癌基因 与髓细胞组织增生症病毒同源的原癌基因 伯基特氏淋巴瘤 伯基特淋巴瘤 全血或组织;血液/组织;血液或组织 分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 基因突变分析 存在;存在与否;特征标识;身份;身份标识 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因 骨髓细胞瘤病毒同源原癌基因 髓细胞瘤病毒同源原癌基因 髓细胞组织增生病毒同源原癌基因 髓细胞组织增生症病毒同源原癌基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=42794-8