Version 2.77

Part Description

LP36372-8   Bile acid fractions panel
Bile acids (BAs) play a primary role in digesting dietary fats. Primary BAs are produced in the liver by either the classic or alternative pathway. CYP7A1 controls the production of primary BAs in the liver. The primary BAs (chenodeoxycholic acid and cholic acid) are conjugated to either glycine or taurine to create conjugated primary BAs, which are stored in the gallbladder. Once released into the intestinal circulation, primary BAs are modified by gut bacteria (e.g., deconjugated) to form secondary BAs. Secondary BAs are actively reabsorbed in the terminal ileum, and travel back to the liver through the portal circulation. PMID: 28249284

Different disorders are associated with various patterns of primary and secondary BA levels. Examples of disorders and their associated BA patterns include:
Disorders of BA synthesis (information from PMID: 18577977):
1) Inborn errors of bile acid synthesis including cerebrotendinous xanthomatosis, Zellweger syndrome, and a variety of other enzyme deficiencies - low or absent BAs
2) Bile acid conjugation defects - increased levels of unconjugated cholic and deoxycholic acid, lack of chenodeoxycholic acid

Disorders of BA metabolism (information from PMID: 28249284):
1) Inflammatory bowel disease - reduced deconjugation by gut bacteria, lower levels of secondary BAs
2) Irritable bowel syndrome - reduced deconjugation, increased levels of primary conjugated BAs, lower levels of secondary BAs
3) Short bowel syndrome - reduced levels of secondary and tertiary BAs
4) Obesity - lower levels of both primary BAs Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
43130-4 Bile acid fractions panel [Moles/volume] - Serum or Plasma
Indent14628-2 Bile acid [Moles/volume] in Serum or Plasma R umol/L
Indent38187-1 Bile acid.dihydroxy [Moles/volume] in Serum or Plasma umol/L
Indent38188-9 Bile acid.trihydroxy [Moles/volume] in Serum or Plasma umol/L
Indent30519-3 Chenodeoxycholate [Moles/volume] in Serum or Plasma umol/L
Indent30518-5 Cholate [Moles/volume] in Serum or Plasma umol/L
Indent30520-1 Deoxycholate [Moles/volume] in Serum or Plasma umol/L
Indent53479-2 Dihydroxycholestanoate [Moles/volume] in Serum or Plasma umol/L
Indent93335-8 Glycochenodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93334-1 Glycocholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93333-3 Glycodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93332-5 Glycohyodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93331-7 Glycolithocholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93330-9 Glycoursodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93329-1 Hyodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent74897-0 Lithocholate [Moles/volume] in Serum or Plasma umol/L
Indent93328-3 Taurochenodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93327-5 Taurocholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93326-7 Taurodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93325-9 Taurohyodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93324-2 Taurolithocholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93323-4 Tauroursodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent55159-8 Ursodeoxycholate [Moles/volume] in Serum or Plasma umol/L
Indent75038-0 Bile acid pattern [Interpretation] in Serum or Plasma Narrative

Fully-Specified Name

Component
Bile acid fractions panel
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Bile Acid Fract Pnl SerPl-sCnc
Display Name
Bile acid fractions panel [Moles/Vol]
Consumer Name Alpha Get Info
Bile acid fractions panel, Blood

Basic Attributes

Class
PANEL.CHEM
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.73
Change Reason
Release 2.67: SYSTEM: Added Plas to be consistent with the terms contained in the panel
Order vs. Observation
Order
Common Test Rank Get Info
7431
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel ácidos biliares fraccionados:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Panel de fracciones de ácidos biliares:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FR French (France) Acides biliaires fractions panel:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Acido biliare, panel frazionato:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Acidi biliari Chimica Concentrazione di Sostanza Panel frazionato acidi biliari Plasma Punto nel tempo (episodio) Set di prescrizione chimica Siero Siero o Plasma
nl-NL Dutch (Netherlands) galzuren fracties panel:mol/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Ácidos biliares fracionados painel:SCnc:Pt:Soro:Qn:
Synonyms: ; Bile Acid Fract Pnl; Bile salt; Bile acid.total; Substance concentration; Level; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Pan; Panl; Frac; Fraction; Acd; Acids; PANEL.CHEMISTRY; PANEL.CHEMISTRY; Chemistry
ru-RU Russian (Russian Federation) Желчные кислоты фракционированные панель:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Желчные кислоты Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Safra asidi fraksiyonlamış panel:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 胆汁酸类成分组套:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: BA;TBA;总胆汁酸;胆汁酸.总计;胆汁酸盐;胆盐 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 分数类 分级 分级分离 分部分离 分馏 分馏（Fractionation） 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.化学试验;化学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;化学医嘱组类;医嘱组.化学;医嘱组.化学检验项目;医嘱组类.化学;医嘱组类.化学检验项目;医嘱组类.化学试验;实验室医嘱组类.化学;实验室医嘱组类.化学检验项目;实验室医嘱组类.化学试验 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 精汁;胆;胆液 精馏 组 组份类（Fractions） 组分类 组合 组合医嘱 组合类 组套 胆汁酸分离医嘱组;胆汁酸分类医嘱组;胆汁酸分级医嘱组;胆汁酸鉴别医嘱组;胆汁酸分馏医嘱组;胆汁酸馏分医嘱组;分馏型胆汁酸组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;胆汁酸成分（组分、组份、成份）医嘱组 血清或血浆 部分类 酸 馏分类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43130-4
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/43130-4