Version 2.77

Part Description

LP16714-5   Histone
Histones are small nuclear proteins that together with dsDNA, represent a nucleosome, the structural unit of chromatin. Anti-histone antibodies are associated with various autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, infectious diseases (including HIV), and some neurological disorders such as Alzheimer's disease and dementia. Nearly all patients with drug-induced SLE have anti-histone antibodies, but they are also present in patients with idiopathic forms of the disease. One study showed a correlation between SLE with positive anti-dsDNA, anti-nucleosome and anti-histone antibodies and renal disease, including proliferative glomerulonephritis. PMID: 24649358 Source: Regenstrief LOINC, PMID: 24649358

Fully-Specified Name

Component
Histone Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
Histone Ab Ser IA-aCnc
Display Name
Histone Ab IA Qn (S)
Consumer Name Alpha Get Info
Histone antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
3520

Member of these Groups Get Info

LOINC Group Group Name
LG12062-2 Histone Ab|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Histon-AK EIA
de-DE German (Germany) Histon Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Immunoassay
es-ES Spanish (Spain) Histona Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Histona Ab:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Histoon antikehad:Acnc:Pt:S:Qn:IA
Synonyms: Juhuslik Kvantitatiivne Seerum
fr-CA French (Canada) Histone , Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR French (France) Histones anticorps:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE French (Belgium) Histone Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
Synonyms: Anticorps
it-IT Italian (Italy) Istone Ab:ACnc:Pt:Siero:Qn:IA
Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) histon As:eenheid/volume:moment:serum:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
pt-BR Portuguese (Brazil) Histona Ac:ACnc:Pt:Soro:Qn:Imunoensaio
Synonyms: Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) Гистон Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:IA
Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Histon Ab:SçKons:Zmlı:Ser:Kant:İA
Synonyms: Ak İmmünölçüm, immünoassay
zh-CN Chinese (China) 组蛋白 抗体:任意型浓度:时间点:血清:定量型:免疫测定法
Synonyms: Ab;自身抗体 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 组朊 组朊 Ab 组朊抗体 组蛋白 Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43231-0